D,L-β-Aminoisobutyric Acid Analysis Service

D- and L-β-Aminoisobutyric Acid (D- and L-β-AIBA) are byproducts of pyrimidine metabolism present in various organisms. These stereoisomers are important in metabolic regulation and serve as biomarkers for muscle metabolism and energy balance. Changes in D- and L-β-AIBA levels may be linked to conditions such as diabetes, obesity, and certain cancers. Accurate measurement of D- and L-β-AIBA concentrations is essential for understanding their roles in different health states and providing a basis for diagnosing and treating related diseases.

 

 



Figure 1. Molecular Structure of β-AIBA

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of D- and L-β-AIBA and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of D- and L-β-AIBA in complex biological matrices.

 

Analysis Workflow

 

 

 

Service Advantages

1. High Sensitivity and Precision

HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of β-AIBA and differentiating its isomers.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

 

 

For detailed sample submission instructions, please consult our technical team.

 

Applications

Clinical Diagnosis: Measure D- and L-β-AIBA levels in patients with diabetes, obesity, and certain cancers to assist in diagnosis and prognosis.

 

Metabolic Research: Investigate the roles of D- and L-β-AIBA in pyrimidine metabolism and their metabolic regulation.

 

Drug Development: Evaluate the impact of drugs on D- and L-β-AIBA metabolism to aid in developing new therapeutic agents.

 

Nutritional Research: Analyze the metabolic changes of D- and L-β-AIBA under different dietary conditions, providing scientific evidence for nutritional regulation and dietary supplementation.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on D,L-β-AIBA and their Metabolites

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into D,L-β-AIBA's extensive physiological roles through top-tier analytical techniques and expert services.