Multi-Omics Services
As biological research continues to evolve, single-omics approaches are no longer sufficient to fully capture the complexity of biological systems. MtoZ Biolabs offers Multi-Omics Services that encompass proteomics, metabolomics, lipidomics and transcriptomics to provide a comprehensive understanding of biological processes. Leveraging advanced technology platforms, we offer high-resolution, high-throughput data analysis to uncover disease mechanisms, explore drug targets, and discover biomarkers.
Hayes, N. et al. Genes. 2024.
Figure 1. Multi-omics Concepts
Services at MtoZ Biolabs
With our nano LC-MS/MS platforms and high-resolution mass spectrometry technology, combined with methods like Labe-Free, iTRAQ, TMT, SILAC, and DIA, we provide precise identification and quantification of complex protein samples. In addition, MtoZ Biolabs uses the Bruker timsTOF HT system for 4D proteomics analysis, offering deep insights into post-translational modifications (PTMs), protein interaction networks, and functional states. This supports drug development and biomarker screening.
Using GC-MS, LC-MS, and NMR, we precisely analyze metabolites, including small molecules, lipids, amino acids, sugars, and nucleotides. We use GC-MS for volatile metabolites, LC-MS for complex sample analysis, and NMR for structural elucidation. This service aids in the study of metabolic pathways, drug metabolism, and mechanisms of metabolism-related diseases, providing precise data for drug development.
Using advanced mass spectrometry technologies like Thermo Fisher Orbitrap Fusion Lumos and Q Exactive HF, combined with Nano-LC, we offer high-precision, high-throughput lipidomics analysis. Our services enable the comprehensive analysis of lipid composition, structure, and metabolism, providing critical insights into lipid metabolism pathways and their biological roles in disease mechanism research, biomarker discovery, and drug target development.
Transcriptome Sequencing (RNA-sequencing) Service
With RNA-Seq, we perform complete transcriptomic analysis for both prokaryotes and eukaryotes, capturing dynamic gene expression changes and uncovering transcriptional regulatory mechanisms. This service helps clients discover new drug targets, disease mechanisms, and biomarkers, providing key data for precision medicine and clinical research.
Multi-Omics Integrative Services
By integrating data from genomics, proteomics, metabolomics, and transcriptomics, we use systems biology approaches to reveal interactions across different omics layers. This allows MtoZ Biolabs to provide customers with a comprehensive understanding of biological processes and disease mechanisms, advancing precision medicine and drug development.
Using advanced algorithms and computational platforms, we process and interpret large-scale omics data. Our services include data mining, functional annotation, and pathway analysis, helping clients extract meaningful biological insights, identify potential biomarkers, disease mechanisms, and drug targets, supporting precision medicine and clinical applications.
Through 10x Genomics Chromium and Illumina platforms, we provide single-cell transcriptomics, proteomics, and metabolomics analysis, allowing for the study of gene expression, protein composition, and metabolic states in individual cells. MtoZ Biolabs uses single-cell analysis technologies to reveal heterogeneity between cells, immune responses, tumor microenvironments, and more, providing crucial data for immunotherapy, cancer research, and personalized medicine.
Analysis Workflow
Service Advantages
✅ Advanced Equipment and Technology Platforms
Equipped with cutting-edge mass spectrometry and chromatography systems, we ensure high resolution and sensitivity at every step of the experiment, providing reliable data support.
✅ Integration of Multiple Methods
By combining Label-Free, iTRAQ, TMT, SILAC, DIA, and other methods, we provide customized analysis services to meet diverse research needs.
✅ Post-Translational Modifications and Interaction Studies
With expertise in PTMs and protein interaction networks, we offer in-depth biological insights for clients.
✅ Professional Team with Extensive Experience
Our experienced team of scientists is proficient in various omics techniques, offering precise experimental design and data analysis.
✅ Comprehensive Technical Support
We provide not only experimental data but also detailed reports and biological interpretations to help clients understand their results and apply them in further research.
✅ One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
Deliverables
· Experimental data: Raw MS/Flow/Sequencing files (RAW, Wiff, FCS, Fastq, etc.)
· Sample QC reports and methodology descriptions
· Tabular results: Modification sites, impurity concentrations, immune profiles, etc.
· Visualization and summary reports: Glycan distribution maps, enrichment
· Data analysis summary reports: Ready-to-use figures and captions for publications and project applications
MtoZ Biolabs provides customized Multi-Omics Services, helping you unlock key biological insights in disease research, drug development, and personalized medicine. For more information or project consultations, please contact us for a tailored project plan and expert support.
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider.
Related Services
Integrative Proteomics-Metabolomics Analysis Service
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