Targeted Lipidomics Analysis Service

Lipids, small molecules that are either hydrophobic or amphipathic, include fats, waxes, sterols, and fat-soluble vitamins (vitamin A, D, E, and K), monoacylglycerides, diacylglycerides, and phospholipids. In biological physiology, lipids play crucial roles not only in  energy storage and structural components of cellular membranes but also in facilitating signal transduction, membrane transporting, and morphogenesis.

 

MtoZ Biolabs offers comprehensive Targeted Lipidomics Analysis Service, utilizing advanced tandem mass spectrometry and a cutting-edge bioinformatics platform. Our experienced team employs high-resolution mass spectrometry in combination with isotope-labeled standards to ensure precise and accurate quantification of lipid molecules. Specifically, we utilize parallel reaction monitoring (PRM) technology to selectively capture the signals of target lipid species, enabling their absolute quantification. This approach not only enhances the sensitivity and specificity of lipid detection but also ensures robust and reproducible results, making it ideal for targeted lipid validation in complex biological samples. Our services meet the stringent demands of lipidomics research by delivering high-quality data for both exploratory studies and targeted investigations.

 

Services at MtoZ Biolabs

1. Fatty Acid Analysis Services

(1) ω-3 fatty acids

(2) ω-6 fatty acids

(3) Free fatty acids

(4) Esterified fatty acids

(5) Total fatty acids

(6) Trans fatty acids

(7) Short-chain fatty acids

(8) Medium-chain and long-chain fatty acids

(9) Very long-chain fatty acids

(10) Straight-chain and branched-chain fatty acids; Saturated fatty acids

 

2. Fatty Acid Derivatives Analysis Services

(1) Prostaglandins

(2) Leukotrienes

(3) Eicosanoids and their metabolites (urine)

(4) CYP450 enzyme metabolites

(5) Hydroxy-eicosatetraenoic acids

(6) Lipoxygenase products

(7) Endocannabinoids

(8) Mycolic acids

 

3. Fatty Acid Metabolism Analysis Services

(1) Fatty acid metabolism

(2) Acyl-coAs

 

4. Glycerolipid Analysis Services

(1) Glycerolipids

(2) Diacylglycerols

(3) Triglycerides

 

5. Glycerophospholipid Analysis Services

(1) Glycerophospholipids

(2) Cardiolipins

 

6. Sphingolipid Analysis Services

(1) Ceramides; Sphingomyelins

(2) Sphingosine bases

(3) Gangliosides

(4) Sphingolipid metabolism

(5) Phosphate 1 phosphate

(6) Hexosylceramides

 

7. Isoprenoid Analysis Services

Polyprenols

 

8. Sterol Analysis Services

(1) Total cholesterol; Free cholesterol

(2) Cholesterol esters

(3) Oxysterols; Steroids

 

9. Additional Analysis Services

(1) Lipid classes; Phospholipids

(2) Wax esters

(3) Olive oil phenols

 

Service Advantages

1. Broad Applicability

No species restrictions and no need for reference standards (as the majority of lipids lack available standards).

 

2. High Throughput

Capable of detecting dozens of lipid molecules in a single run, significantly reducing sample and experimental costs.

 

3. Robust Quantification

Offers exceptional sensitivity, reaching ppm levels, with a linear range spanning 5-6 orders of magnitude.

 

Sample Submission Requirements

 



For more sample details, please consult our technical team.