N'-Formylkynurenine Analysis Service

N'-Formylkynurenine is a crucial intermediate in the tryptophan metabolism pathway, playing significant roles in various biological processes. It is produced enzymatically from tryptophan and is part of the kynurenine pathway, vital for antioxidant defense and immune regulation. Changes in N'-Formylkynurenine levels are linked to neurodegenerative diseases, cancer, and immune disorders. Therefore, accurate analysis of N'-Formylkynurenine is essential for understanding its biological mechanisms and potential disease applications.

 



Figure 1. Molecular Structure of N'-Formylkynurenine

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of N'-Formylkynurenine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of N'-Formylkynurenine in complex biological matrices.

 

Analysis Workflow

 

 

 

Service Advantages

1. High Sensitivity and Precision

HPLC-MS/MS provides highly sensitive and accurate measurements, suitable for detecting low concentrations of N'-Formylkynurenine.

 

2. Rapid and Efficient

Optimized sample preparation and fast analysis ensure quick and efficient processing.

 

3. Wide Applicability

Suitable for various biological samples, including blood, urine, and tissues.

 

4. Accurate and Reliable Data

Ensures high reproducibility and low error rates, supporting both research and clinical applications, providing reliable and specific results.

 

Sample Submission Requirements

 

 

For detailed sample submission instructions, please consult our technical team.

 

Applications

Neurodegenerative Disease Research: Analyze changes in N'-Formylkynurenine levels to study its role in neurodegenerative diseases like Alzheimer's and Parkinson's.

 

Cancer Research: Evaluate N'-Formylkynurenine levels in different cancer types to explore its potential as a cancer biomarker.

 

Immune Regulation Research: Study the role of N'-Formylkynurenine in the immune system and its applications in immune-related diseases.

 

Antioxidant Defense Research: Analyze the role of N'-Formylkynurenine in cellular antioxidant defense and explore its potential in developing antioxidants.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on N'-Formylkynurenine and Their Metabolites

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into N'-Formylkynurenine's extensive physiological roles through top-tier analytical techniques and expert services.