1-Methylhistidine Analysis Service
- Nutritional Research: Assess dietary protein intake and digestion.
- Sports Medicine: Monitor muscle protein metabolism and damage.
- Renal Function Research: Investigate 1-Methylhistidine metabolism in renal insufficiency.
- Clinical Nutrition: Evaluate the metabolic status of malnourished patients.
1-Methylhistidine is a metabolite formed by the methylation of histidine, primarily found in muscle tissue. It plays a crucial role in protein metabolism and serves as a biomarker for muscle protein degradation and dietary protein intake. Variations in 1-Methylhistidine levels are linked to several physiological and pathological conditions, such as muscle atrophy, renal insufficiency, and malnutrition. Analyzing 1-Methylhistidine and its metabolites provides valuable insights into their roles in health and disease, aiding in prevention, diagnosis, and treatment.
Figure 1. Molecular Structure of 1-Methylhistidine
MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of 1-Methylhistidine and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of 1-Methylhistidine in complex biological matrices.
Analysis Workflow
Service Advantages
Sample Submission Requirements
For detailed sample submission instructions, please consult our technical team.
Applications
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 1-Methylhistidine and Their Metabolites
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into 1-Methylhistidine's extensive physiological roles through top-tier analytical techniques and expert services.
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