1-Methylxanthine Analysis Service

1-Methylxanthine is a methylated derivative of xanthine, a purine base found in most human tissues and other organisms. Its structure consists of a xanthine core with a methyl group attached to the nitrogen at the 1-position of the imidazole ring. This class of compounds is known for its stimulatory effects on the central nervous system and its ability to act as adenosine receptor antagonists. 1-Methylxanthine is a metabolic product in the caffeine metabolism process, formed by the enzyme cytochrome P450 1A2 (CYP1A2). 

 

1-Methylxanthine is commonly used in research to study the metabolism of methylxanthines, particularly in the context of caffeine metabolic pathways and enzyme activity. Although 1-methylxanthine itself is not widely used therapeutically, understanding its metabolism and effects can help form the basis for developing treatment strategies for conditions such as asthma, COPD, and metabolic disorders. It is frequently measured in clinical studies to assess an individual's caffeine metabolism rate, which is relevant in pharmacogenetic research.

 



Figure 1. The Structure of 1-Methylxanthine

 

At MtoZ Biolabs, we offer a leading-edge 1-Methylxanthine Analysis Service, leveraging our advanced LC-MS platform and a team of expert metabolomics. Our service guarantees comprehensive 1-methylxanthine analysis with high sensitivity and accuracy.

 

Analysis Workflow 

 



 

Service Advantages

1. Continuously refined protocols and cutting-edge analytical tools  

 

2. Expert experimental planning  

 

3. Rapid processing times  

 

4. Exceptional precision, selectivity, and sensitivity

 

Applications

• Metabolite qualitative analysis of 1-methylxanthine
• Quantitative analysis of 1-methylxanthine content
• Providing a basis for further improvement in related research

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples. A minimum of 3 samples of the same type is required for each analysis.

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Sample Preservation

Samples should be stored at -80°C to maintain stability.

 

Note: Please provide detailed information on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant LC-MS Parameters

3. Detailed Information on 1-Methylxanthine

4. Raw Data

5. Custom Analysis Report

 

Through our 1-methylxanthine analysis service, we aim to enable your research and product development processes by providing dependable and precise results.