Creatine Analysis Service
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
Creatine is a naturally occurring compound in the human body, primarily stored in muscles. It is synthesized from three amino acids: glycine, arginine, and methionine through a complex biosynthetic pathway. Creatine provides rapid energy supply during high-intensity exercise and strenuous activities through the phosphocreatine pathway. Creatine plays a vital role not only in athletic performance and muscle strength but also in cellular energy metabolism, neuroprotection, and brain function maintenance. Changes in creatine levels are associated with various health conditions, including muscle diseases, cardiovascular diseases, and neurodegenerative diseases. Therefore, accurate analysis of creatine and its metabolites is crucial for understanding its mechanisms in the body and its potential applications in sports science and disease research.
Figure 1. Molecular Structure of Creatine
MtoZ Biolabs offers Creatine Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of creatine in complex biological matrices.
Analysis Workflow
Service Advantages
Sample Submission Requirements
Sample Types
Biological Fluids: Serum, plasma, urine, bile, bile acids
Animal Tissues: Cells, liver, brain, and other animal tissues, as well as feces
Other Samples: Plants, yeast, microorganisms
Sample Volume
At least 200 μL of liquid sample or 200 mg of tissue sample.
Sample Transportation
For shipping, it is recommended to use an adequate amount of dry ice, considering that 3-4 kg of dry ice sublimates in one day. It is advisable to use larger blocks of dry ice as they sublimate more slowly. Ensure samples are sealed in a foam box and opt for the fastest possible shipping method to minimize sample degradation during transport.
Applications
Sports Science Research: Analyze changes in creatine levels to study its role in athletic performance and fatigue delay.
Neuroprotection Research: Evaluate changes in creatine levels in neuroprotection and neurodegenerative diseases, studying its potential role in neural health.
Cardiovascular Disease Research: Investigate the role of creatine in cardiovascular health and diseases, exploring its applications in myocardial protection and function improvement.
Metabolic Disease Research: Analyze changes in creatine levels in metabolic diseases, studying its role in diabetes and metabolic syndrome.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Creatine
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into creatine's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
