Drug Toxicity Assessment Service
- Drug Hepatotoxicity Evaluation: Assessing the potential liver toxicity of pharmaceuticals to ensure safety regarding liver function.
- Drug Nephrotoxicity Evaluation: Evaluating the impact of drugs on kidney health and their potential to cause renal toxicity.
- Drug Neurotoxicity Testing: Testing for adverse effects of pharmaceutical compounds on the nervous system to prevent neurotoxic risks.
- Blood Sample: At least 2ml, preserved at -80℃, avoid repeated freeze-thaw.
- Urine Sample: At least 5ml, preserved at -80℃, avoid repeated freeze-thaw.
- Cell Sample: At least 1×106 cells, preserved at -80℃, avoid repeated freeze-thaw.
Drug toxicity is a critical issue that must be addressed in the process of drug development. Inappropriate drug toxicity can lead to the failure of drug development and even pose a threat to the patient's health. Therefore, drug toxicity assessment is crucial for the development, safety, and efficacy of drugs. MtoZ Biolabs provides comprehensive drug toxicity assessment services, using mass spectrometry metabolomics technology, combined with our extensive experience and advanced technical platform, we provide the most reliable and comprehensive drug toxicity assessment results for customers.
Estevan, C. et al. InTech. 2011.
Figure1. Role of Stem Cells in Toxicity Testing
Services at MtoZ Biolabs
As an industry leader, MtoZ Biolabs offers comprehensive toxicity assessment services from the molecular to the systemic level. Our team is composed of experienced toxicologists and analytical chemists who excel in utilizing advanced analytical techniques and bioinformatics tools to provide scientifically rigorous, data-driven evaluation reports. Our drug toxicity assessment services include, but are not limited to:
Analysis Workflow
1. Sample Preparation: We accept a variety of sample types, including blood, urine, cells, etc.
2. Sample Extraction: Choose the appropriate method for metabolite extraction according to the sample type.
3. Analysis: Use High Performance Liquid Chromatography-Mass Spectrometry (LC-MS) for metabolite analysis.
4. Data Processing: Use specialized software for data processing and statistical analysis to identify significantly different metabolites.
5. Interpretation: Based on our extensive metabolite database and bioinformatics tools, interpret the results to reveal the mechanism of action and toxic effects of drugs.
Service Advantages
1. High sensitivity and accuracy: Our LC-MS platform can detect thousands of metabolites, providing highly sensitive and accurate results.
2. Extensive experience: We have extensive experience in drug toxicity assessment and can provide reliable services for customers.
3. Comprehensive database and tools: We have a comprehensive metabolite database and bioinformatics tools that can provide in-depth analysis and interpretation.
4. Multi-level Assessment Methods: We combine in vitro, in vivo, and molecular biology techniques to provide multidimensional scientific evidence for drug safety.
5. Rapid Response and Customized Services: Based on the characteristics of the drug and project requirements, we swiftly design and execute toxicity assessment plans.
6. Adherence to International Standards: All tests and evaluations strictly follow the guidelines of international regulatory agencies such as the FDA and EMA.
Sample Submission Requirements
MtoZ Biolabs' drug toxicity assessment services are designed to provide comprehensive, efficient, and regulation-compliant safety evaluations, aiding the smooth transition of drug candidates to the clinical development stage. If you have any other questions, please feel free to contact us.
How to order?
