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    Medroxyprogesterone Acetate Analysis Service

      Medroxyprogesterone acetate (MPA) is a synthetic derivative of the naturally occurring steroid hormone progesterone. Its structural characteristics include an acetate group introduced at the 17α position and a methyl group at the 6α position on the progesterone backbone, with a chemical formula of C24H34O4 and a molecular weight of approximately 386.53 g/mol. MPA is a versatile synthetic progestogen with a wide range of clinical applications, including hormone replacement therapy, contraception, and cancer treatment. Given the widespread use of medroxyprogesterone acetate (MPA) in therapy, quantitative analysis of its levels in plasma or body fluids is essential to ensure therapeutic efficacy. By monitoring the concentration of MPA, it is possible to maintain effective drug levels in patients while avoiding potential toxicity. This is particularly important for patients on long-term medication, such as those using MPA for hormone replacement therapy or contraception. Analyzing the levels of MPA and its metabolites helps to understand its metabolic processes and elimination pathways in the body. These data can further optimize drug dosage and administration regimens, predict potential drug interactions, and provide a basis for drug development and clinical application.

       

      High-performance liquid chromatography (HPLC), often coupled with mass spectrometry (LC-MS), is commonly used for the quantitative determination of MPA in biological samples such as plasma and urine. This method offers high sensitivity, specificity, and accuracy, making it particularly suitable for pharmacokinetic studies, therapeutic drug monitoring, and clinical research.

       

      1834435790626213888-TheStructureofMedroxyprogesteroneAcetate.png

      Figure 1. The Structure of Medroxyprogesterone Acetate

       

      Our Medroxyprogesterone Acetate Analysis Service at MtoZ Biolabs utilizes our advanced liquid chromatography-mass spectrometry (LC-MS) platform, which is managed by our expert metabolomics team. Our service offers a comprehensive and detailed analysis of medroxyprogesterone acetate to meet researchers' needs.

       

      Analysis Workflow

       

      1834435827657723904-WorkflowofMedroxyprogesteroneAcetateAnalysisService.PNG

       

      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms.
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      • Improved understanding of medroxyprogesterone acetate's pharmacological effects
      • Development of new therapeutic strategies
      • Rapid identification of potential disease biomarkers
      • In-depth exploration of disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. At least 3 samples of the same type and under the same condition are required for each sample. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C for optimal stability.

       

      Note: Please include details of sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Medroxyprogesterone Acetate

      4. Raw Data

      5. Custom Analysis Report

       

      With our Medroxyprogesterone Acetate Analysis Service, we strive to support your research and product development by providing accurate and dependable results. Trust MtoZ Biolabs for all your metabolomics analysis needs.

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