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    N4-acetylcytidine Analysis Service

      N4-acetylcytidine (ac4C) is a modified nucleoside found in tRNAs and rRNAs of a wide range of organisms including bacteria, yeast, and humans. Structurally, ac4C is cytidine with an acetyl group at the 4th nitrogen position of its cytosine base. The addition of this acetyl group is facilitated by NAT10, a N-acetyltransferase enzyme in humans.

       

      N4-acetylcytidine plays crucial roles in regulating cellular processes such as protein synthesis, maintenance of chromosomal stability. The study of N4-acetylcytidine is of profound significance due to its potential to serve as a diagnostic and prognostic biomarker for a variety of diseases, including cancer. Alterations in its levels have been correlated with disease states, thus, its accurate detection and quantification can provide valuable insights into disease mechanisms and potential therapeutic strategies.

       

      1834117060968960000-TheStructureofN4-acetylcytidine.png

       

      Figure 1. The Structure of N4-acetylcytidine

       

      MtoZ Biolabs now provides N4-acetylcytidine Analysis Service to our clients. We are equipped with cutting-edge mass spectrometry instruments and have a highly skilled team of scientists experienced in N4-acetylcytidine analysis. We offer comprehensive N4-acetylcytidine analysis including qualitative and quantitative analysis, providing you with accurate and reliable results.

       

      Analysis Workflow

       

      1834112944305721344-WorkflowforN4-acetylcytidineAnalysisService.png

       

      Service Advantages

      • Rapid Analysis Cycle and Cost-Effectiveness
      • Stable, Reliable, and Highly Sensitive Results
      • Comprehensive One-Stop Service for Extensive Testing Needs
      • User-Friendly Operation with Wide Application Scope
      • Supported by Extensive Bioanalytical Resources and Advanced Platforms

       

      Applications

      Our N4-acetylcytidine analysis service can be applied in various fields including, but not limited to: 

      • Biomarker discovery
      • Disease diagnostics
      • Therapeutic development

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Storage and Shipping

      Samples should be stored at -80℃ and shipped with dry ice.

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on N4-acetylcytidine

      4. Raw Data

      5. Custom Analysis Report

       

      At MtoZ Biolabs, we are committed to providing you with exceptional N4-acetylcytidine analysis services. Contact us to learn more about how we can assist you in your research.

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