Nicotinuric Acid Analysis Service

Nicotinuric acid (NUA) is a crucial amino acid derivative synthesized in the body from niacin and glycine. Specifically, niacin is first converted into nicotinamide, which then combines with glycine to form NUA. As a metabolite of niacin, NUA plays significant roles in various biological processes, including antioxidant, anti-inflammatory, and metabolic regulation. Changes in its levels are closely associated with various health conditions, such as metabolic syndrome, diabetes, and cardiovascular diseases. Therefore, accurate measurement and monitoring of NUA levels are essential for disease research and diagnosis.

 



Figure 1. Molecular Structure of Nicotinuric Acid

 

MtoZ Biolabs offers Nicotinuric Acid Analysis Service using liquid chromatography-tandem mass spectrometry (LC-MS/MS). This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of NUA in complex biological matrices.

 

Analysis Workflow

 



 

Service Advantages

 



 

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

 

Sample Preservation

Store and transport samples at -80 °C.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on NUA

4. Raw Data

5. Custom Analysis Report

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into NUA's extensive physiological roles through top-tier analytical techniques and expert services.