Proline Analysis Service

Proline (Pro) is one of the twenty standard amino acids in proteins, crucial for plant stress tolerance and animal metabolic regulation. It plays pivotal roles in various biochemical processes including protein synthesis, cell wall stability, and antioxidative responses. In clinical contexts, proline's metabolic anomalies are closely linked to a range of diseases such as liver disorders, metabolic syndromes, and genetic conditions. Thus, precise measurement of proline levels and metabolic activity is essential for diagnosing diseases, monitoring treatments, and advancing research.



Figure 1. Molecular Structure of Proline

 

MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of proline and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of proline in complex biological matrices.

 

Analysis Workflow



 

Services at MtoZ Biolabs

Proline Quantitative Analysis

Using advanced LC-MS/MS technology, we precisely measure proline levels in diverse biological samples including tissues, cell cultures, urine, and plasma, ensuring exceptional sensitivity and accuracy.

 

Proline Isotope Labeling Analysis

Our stable isotope labeling technique offers detailed insights into proline's metabolic dynamics, allowing researchers to track its utilization and transformation within biological systems.

 

Proline Metabolite Analysis

We provide an extensive analysis of proline-related metabolites, offering a thorough perspective on proline's metabolic pathways and identifying potential biomarkers and key signaling molecules.

 

Service Advantages



 

Sample Submission Requirements

 

For detailed sample submission instructions, please consult our technical team.

 

Applications

Disease Diagnosis: Tracking proline variations aids in diagnosing and evaluating liver and kidney diseases.

 

Drug Metabolism Studies: Investigating proline's role in drug metabolism helps optimize therapeutic designs and regimens.

 

Nutritional and Metabolic Studies: Evaluating proline's metabolic adjustments across different nutritional states informs dietary supplementation and modifications.

 

Genetic Disease Research: Studying proline metabolism anomalies enhances our understanding of genetic metabolic disorders, contributing to etiological advancements.

 

MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into proline's extensive physiological roles through top-tier analytical techniques and expert services.