Trans-4-Hydroxy-L-Proline Analysis Service
- Liquid Chromatography-Mass Spectrometry (LC-MS)
- Gas Chromatography-Mass Spectrometry (GC-MS)
- Liquid Chromatography-Tandem Mass Spectrometry (LC-MS/MS)
Trans-4-Hydroxy-L-Proline (T4H-L-Pro) is a crucial amino acid derivative essential for collagen structure, playing a key role in its stability and integrity. Changes in T4H-L-Pro levels can be linked to conditions such as connective tissue diseases, osteoarticular diseases, and skin disorders. Accurate measurement of T4H-L-Pro concentrations provides insights into its biological roles, aiding in the diagnosis and treatment of related conditions.
Figure 1. Molecular Structure of T4H-L-Pro
MtoZ Biolabs utilizes liquid chromatography-tandem mass spectrometry (LC-MS/MS) to conduct detailed quantitative and qualitative analyses of T4H-L-Pro and its metabolites. This advanced method integrates LC's rapid separation capabilities with the high detection sensitivity of MS/MS, facilitating the precise measurement of T4H-L-Pro in complex biological matrices.
Analysis Workflow
Experimental Instruments
Service Advantages
Sample Submission Requirements
Please ensure that the sample volume is greater than 0.2 g or 0.2 mL.
Applications
Clinical Diagnosis: Measure T4H-L-Pro levels in patients with connective tissue diseases, osteoarticular diseases, and skin disorders to assist in diagnosis and prognosis.
Metabolic Research: Investigate the roles of T4H-L-Pro in collagen metabolism and stability.
Drug Development: Evaluate the impact of drugs on T4H-L-Pro metabolism to aid in developing new therapeutic agents.
Nutritional Research: Analyze the metabolic changes of T4H-L-Pro under different dietary conditions, providing scientific evidence for nutritional regulation and dietary supplementation.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on T4H-L-Pro
4. Raw Data
5. Custom Analysis Report
MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into T4H-L-Pro's extensive physiological roles through top-tier analytical techniques and expert services.
How to order?
