Bile acids
- Rapid Analysis Cycle and Cost-Effectiveness
- Stable, Reliable, and Highly Sensitive Results
- Comprehensive One-Stop Service for Extensive Testing Needs
- User-Friendly Operation with Wide Application Scope
- Supported by Extensive Bioanalytical Resources and Advanced Platforms
Bile acids are the end products of cholesterol metabolism, synthesized primarily by the liver, and play crucial roles in the intestine. They are essential for lipid digestion and absorption, participate in the enterohepatic circulation, and regulate physiological processes such as energy metabolism, glucose and lipid metabolism, and inflammation. Abnormal bile acid metabolism is closely associated with various diseases, including liver diseases, gallbladder diseases, and metabolic syndrome. Accurate analysis of bile acids and their metabolites is essential for understanding their roles in health and disease.
Figure 1. The Structures of the Principal Human Bile Acids
MtoZ Biolabs uses ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) for bile acid analysis. This advanced technology combines efficient UPLC separation with sensitive MS detection, ensuring accurate identification and quantification of various bile acids and their metabolites in complex biological samples.
Analysis Workflow
Service Advantages
Sample Submission Requirements
Applications
1. Liver and Biliary Disease Research: Aid in diagnosing and evaluating liver and biliary diseases by monitoring bile acid levels.
2. Metabolic Research: Investigate the role of bile acids in cholesterol metabolism and fat digestion, revealing mechanisms in metabolic syndrome.
3. Gut Microbiome Research: Analyze the impact of gut microbiota on bile acid metabolism, exploring their role in gut health.
4. Drug Development: Evaluate the effects of new drugs on bile acid metabolism, aiding in developing therapies targeting bile acid pathways.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Bile Acids
4. Raw Data
5. Custom Analysis Report
How to order?
