11-Deoxycortisol Analysis Service

11-Deoxycortisol is a steroid hormone produced by the adrenal gland, serving as a crucial intermediate in the cortisol synthesis pathway. As a precursor to glucocorticoids, 11-deoxycortisol is converted into cortisol in the body through the action of 11β-hydroxysteroid dehydrogenase, which is essential for metabolism, immune regulation, and stress response. Measuring 11-deoxycortisol levels is clinically significant for assessing adrenal function, diagnosing congenital adrenal hyperplasia (CAH), and monitoring the efficacy of related treatments.

 

Figure 1. Molecular Structure of 11-Deoxycortisol

 

MtoZ Biolabs offers 11-Deoxycortisol Analysis Service using high performance liquid chromatography-mass spectrometry (HPLC-MS). This advanced method combines the separation capabilities of HPLC with the detection power of MS, ensuring high sensitivity and specificity in 11-deoxycortisol detection.

 

Analysis Workflow

 



 

Service Advantages

1. High Sensitivity

Detects very low concentrations of 11-deoxycortisol accurately.

 

2. High Specificity

Differentiates 11-deoxycortisol from other compounds using mass spectrometry.

 

3. Rapid Analysis

Efficient sample preparation and fast detection processes for high-throughput analysis.

 

4. High Accuracy

Strict quality control ensures accuracy and reproducibility.

 

5. Versatility

Capable of analyzing 11-deoxycortisol and its related metabolites.

 

Sample Submission Requirements

Make sure the sample volume is greater than 0.2 g or 0.2 mL. For detailed sample submission information, please contact our customer service.

 

Applications

• Essential for assessing adrenal function and diagnosing conditions such as CAH and other endocrine disorders.
• Supports studies on the role of 11-deoxycortisol in glucocorticoid synthesis.
• Facilitates research into the metabolism and pharmacodynamics of drugs related to 11-deoxycortisol.
• Crucial for monitoring the efficacy of related treatments, guiding clinical interventions.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 11-Deoxycortisol

4. Raw Data

5. Custom Analysis Report

 

Our 11-Deoxycortisol Analysis Service provides high-quality data support, advancing your scientific research and applications. For any inquiries or requirements, please contact us.