16α-Hydroxy Estrone Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
16α-Hydroxy estrone is a steroid compound with an aromatic ring structure and is a hydroxylated derivative of estrone (E1) at the 16th carbon position. Its structure contains a phenolic hydroxyl group (-OH) and a hydroxyl group at the 16th position, giving it high polarity and biological activity. 16α-Hydroxy estrone has strong estrogenic activity and is more potent than estrone. It can bind to estrogen receptors (ERα and ERβ), thereby exerting its hormonal effects. Its high estrogenic activity makes it play an important role in regulating the functions of the female reproductive system, skeletal system, and cardiovascular system.
Due to its significant estrogen-promoting effects, 16α-hydroxy estrone may promote cell proliferation and differentiation in specific tissues, such as breast, endometrial, and prostate tissues. Monitoring the levels of 16α-hydroxy estrone in the body may serve as a potential biomarker for certain hormone-related diseases, such as breast cancer and endometrial cancer. Measuring its concentration in urine or blood can help in early diagnosis and risk assessment. Studying the metabolic pathways and regulatory mechanisms of 16α-hydroxy estrone can provide insights into the metabolism of estrogens and their changes under physiological and pathological conditions, thereby offering new strategies for the intervention of metabolic diseases.
Figure 1. The Structure of 16α-Hydroxy Estrone
MtoZ Biolabs provides an innovative 16α-Hydroxy Estrone Analysis Service, employing our advanced liquid chromatography-mass spectrometry (LC-MS) platform and a team of metabolomics experts. We deliver a thorough analysis of 16α-hydroxy estrone, ensuring high sensitivity and precision.
Analysis Workflow
Service Advantages
Applications
1. Evaluating hormone-related diseases and conditions
2. Detecting potential carcinogens
3. Aiding in the development of hormone therapies
4. Enhancing understanding of hormone metabolism and regulation
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. A minimum of 3 samples with similar conditions must be chosen for each analysis.
2. Sample Volume
3. Sample Preservation
To maintain stability, store at -80°C.
Note: Please provide a detailed description of sample collection and handling procedures.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Comprehensive Information on 16α-Hydroxy Estrone
4. Raw Data
5. Custom Analysis Report
With our 16α-hydroxy estrone analysis service, we are committed to delivering accurate and reliable data to support your research and product development projects. If you have any questions or would like to learn more about our analysis services, please feel free to contact us. We look forward to collaborating with you to advance scientific research and clinical applications.
How to order?
