16α-Hydroxyestrone Analysis Service
- Identifying new hormonal biomarkers
- Improving hormonal disease diagnosis
- Accelerating the discovery of novel hormone-based therapeutics
- Gaining new insights into endocrine and metabolic diseases mechanisms
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
16α-Hydroxyestrone (16α-OHE1) is a metabolite of estrogen, produced through the hydroxylation of estrone at the 16α position. Structurally, it features a hydroxyl group added at the C16 position, which distinguishes it from other estrogen metabolites and endows it with unique biological activity. 16α-OHE1 is considered to have pro-estrogenic effects, capable of binding to estrogen receptors and influencing cellular proliferation and differentiation, particularly in breast tissue and other estrogen-related organs. The fluctuations in 16α-OHE1 levels have been closely associated with the incidence of hormone-dependent diseases, such as breast cancer and endometrial cancer. In recent years, 16α-OHE1 has garnered significant research attention as a potential biomarker for cancer. Its levels in the body are closely related to hormonal imbalance and disease risk, particularly when estrogen metabolism is dysregulated. Therefore, quantitative analysis of 16α-OHE1 is crucial for early disease diagnosis, monitoring drug efficacy, and developing personalized treatment plans. Utilizing advanced mass spectrometry techniques, researchers can accurately measure 16α-OHE1 levels and track its metabolic dynamics, providing robust data to explore the complex relationship between hormone metabolism and disease, ultimately advancing research in cancer prevention and treatment of hormone-related disorders.
Figure 1. The Structure of 16α-Hydroxy Estrone
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider, providing advanced metabolomics, proteomics and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of 16α-hydroxyestrone. We ensure the accuracy of the quantification of 16α-hydroxyestrone and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you are interested in our 16α-hydroxyestrone analysis service, please feel free to contact us at any time, and we will be fully committed to providing you with high-quality analytical services and technical support.
Analysis Workflow
Service Advantages
1. Advance Analysis Platform: MtoZ Biolabs established an advanced 16α-hydroxyestrone analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Extensive data coverage with rigorous quality control. Our advanced analysis platform consolidates all 16α-hydroxyestrone analysis data, delivering clients a detailed and comprehensive data report.
4. Quick Turnaround: We offer a fast analysis process to ensure that clients receive high-quality data within a short time.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. More than 3 samples with the same condition should be selected for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental Details （Materials, Instruments and Methods,etc.）
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 16α-Hydroxyestrone Analysis
4. Raw Data
5. Custom Analysis Report
Through our 16α-hydroxyestrone analysis service, we aspire to support your research and product development endeavors by providing accurate and reliable results.
How to order?
