17β-Estradiol Analysis Service | Steroid hormones

17β-Estradiol is the most potent and active form of estrogen steroid hormone in humans, playing a crucial role in regulating the reproductive system and the development of secondary sexual characteristics. It is characterized by a hydroxyl group in the β-configuration at the C17 position, which contributes to its high estrogenic activity. 17β-Estradiol is primarily produced in the ovaries, but it is also synthesized in smaller amounts by other tissues, such as the adrenal glands and adipose tissue. Due to its strong estrogenic activity, 17β-estradiol is essential for various physiological processes, including the regulation of the menstrual cycle, maintenance of pregnancy, bone density, and cardiovascular health. It also influences brain function, mood, and cognitive abilities. However, imbalances in 17β-estradiol levels are associated with several conditions, such as estrogen deficiency in menopause, estrogen dominance in certain cancers, and endocrine disorders.

 

Quantitative analysis of 17β-estradiol and its metabolites is vital for understanding its role in health and disease. It helps in diagnosing and monitoring conditions like estrogen deficiency, hormonal imbalances, and hormone-responsive cancers. Additionally, the analysis of 17β-estradiol levels can guide hormone replacement therapy and assess the effectiveness of treatments for conditions such as osteoporosis, cardiovascular diseases, and breast cancer.

 



Figure 1. The Structure of 17β-Estradiol

 

At MtoZ Biolabs, we are proud to introduce our 17β-Estradiol Analysis Service. This advanced service is based on our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and a team of metabolomics experts. With this service, we provide comprehensive 17β-estradiol analysis, ensuring high sensitivity and accuracy.

 

Analysis Workflow 

 



 

Service Advantages

1. Continuously refined protocols and cutting-edge analytical tools  

 

2. Expert experimental planning  

 

3. Rapid processing times  

 

4. Exceptional precision, selectivity, and sensitivity

 

Applications

• Qualitative and quantitative analysis of 17β-estradiol metabolites
• Analysing the concentration of 17β-estradiol in various biological samples
• Informing the development of hormone therapies and treatments

 

Sample Submission Requirements

1. Sample Types

We accept a range of biological samples including serum, plasma, urine, and tissues. Each sample should be accompanied by at least three materials with the same condition. 

 

2. Sample Volume

• Animal tissue ≥ 100 mg
• Plant tissue ≥ 200 mg
• Serum/ Plasma ≥ 200 μL
• Urine ≥ 2 mL

 

3. Sample Preservation

Samples should be stored at -80°C to maintain stability.

 

Note: Please provide details on how the sample was collected and handled.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 17β-Estradiol

4. Raw Data

5. Custom Analysis Report

 

Through our 17β-estradiol analysis service, our goal is to support your research and product development efforts by providing accurate and reliable results.