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    2-Hydroxyisovaleric Acid Analysis Service

      2-Hydroxyisovaleric acid (HIVA) is a key organic acid and an intermediate in the metabolism of branched-chain amino acids, particularly leucine. It plays a crucial role in energy and amino acid metabolism. Abnormal levels of HIVA may be linked to various metabolic diseases, including organic aciduria, lactic acidosis, and diabetes. Given its importance in metabolic networks, accurate measurement of HIVA in biological samples is essential for studying its metabolic pathways, diagnosing related diseases, and assessing health status.

       1821463385612079104-MolecularStructureof2-HydroxyisovalericAcid.jpg

      Figure 1. Molecular Structure of 2-Hydroxyisovaleric Acid

       

      MtoZ Biolabs offers 2-Hydroxyisovaleric Acid Analysis Service using ultra-performance liquid chromatography-mass spectrometry (UPLC-MS). This advanced method combines the separation capabilities of UPLC with the detection power of MS, ensuring high sensitivity and specificity in HIVA detection.

       

      Analysis Workflow

       

      1821463447385788416-TheWorkflowof2-HydroxyisovalericAcidAnalysis.png

       

      Service Advantages

      • Rapid Analysis Cycle and Cost-Effectiveness
      • Stable, Reliable, and Highly Sensitive Results
      • Comprehensive One-Stop Service for Extensive Testing Needs
      • User-Friendly Operation with Wide Application Scope
      • Supported by Extensive Bioanalytical Resources and Advanced Platforms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissue homogenates, and other biological samples.

       

      2. Sample Volume

      At least 200 μL of liquid sample or 200 mg of solid sample.

       

      3. Sample Preservation

      Store at -80°C to maintain stability.

       

      Note: Provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 2-Hydroxyisovaleric Acid

      4. Raw Data

      5. Custom Analysis Report

       

      MtoZ Biolabs is dedicated to advancing your research and clinical projects by providing detailed insights into HIVA's extensive physiological roles through top-tier analytical techniques and expert services.

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