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    2'-O-methylinosine Analysis Service

      2'-O-methylinosine is a modified nucleoside found in the anticodon loop of tRNA. It is a product of the methylation of inosine, a process catalyzed by a tRNA 2'-O-methyltransferase. The introduction of the 2'-O-methyl group enhances the stability of tRNA and improves the accuracy and efficiency of protein synthesis. Abnormalities in 2'-O-methylinosine levels may be associated with certain diseases, including cancer and neurological disorders. Therefore, understanding 2'-O-methylinosine and its methylation process can provide valuable insights into the regulation of gene expression and disease pathogenesis.

       

      1834782070116306944-TheStructureof2'-O-methylinosine.png

       

      Figure 1. The Structure of 2'-O-methylinosine

       

      At MtoZ Biolabs, we have developed a comprehensive 2'-O-methylinosine analysis service, designed to provide our clients with the most accurate and detailed data. Our team of experienced scientists and cutting-edge technologies allow us to deliver reliable data with great accuracy and precision.

       

      Analysis Workflow

       

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      Service Advantages 

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms. 
      • Strict quality control to ensure reliable results.
      • Comprehensive bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      • Gene expression regulation
      • Disease pathogenesis
      • Drug development
      • Biomarker discovery

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Storage and Shipping

      Samples should be stored at -80℃ and shipped with dry ice.

       

      Note: Please provide details on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Comprehensive Information on 2'-O-methylinosine

      4. Raw Data

      5. Custom Analysis Report

       

      For more information, please contact our customer service. We look forward to supporting your research with our professional and high-quality 2'-O-methylinosine analysis service.

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