2-thio-2'-O-methyluridine Analysis Service
- State-of-the-art mass spectrometry facilities
- Highly experienced and skilled team
- Rigorous data analysis
- Comprehensive and intuitive report
- Competitive pricing
- Basic biological research
- Drug discovery and development
- Biomarker discovery
- Disease diagnosis and prognosis
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
2-thio-2'-O-methyluridine is a modified nucleoside that is found in tRNA and rRNA. The modification is essential for normal growth in eukaryotes and bacteria. Despite the importance of this modified nucleoside, its metabolism and mechanism of action are not fully understood. It originates from the methylation of uridine, a process that is catalyzed by specific enzymes. 2-thio-2'-O-methyluridine is involved in various biological processes such as protein synthesis and transcription regulation.
Figure 1. The Structure of 2-thio-2'-O-methyluridine
2-thio-2'-O-methyluridine has been implicated in various biological processes and diseases. In cancer, the level of this modified nucleoside is often upregulated, suggesting a potential role in tumorigenesis. Moreover, some research has associated changes in the level of 2-thio-2'-O-methyluridine with metabolic disorders, making it an interesting target for therapeutic intervention.
At MtoZ Biolabs, we offer an unrivalled analysis service for 2-thio-2'-O-methyluridine. Leveraging our state-of-the-art mass spectrometry facilities and our extensive expertise in metabolomics, we can assist our clients in elucidating the role of 2-thio-2'-O-methyluridine in various biological processes and diseases.
Analysis Workflow
1. Sample Preparation: Our team of experts will assist in the optimal collection and storage of samples to ensure data quality.
2. 2-thio-2'-O-methyluridine Extraction: Using advanced extraction techniques, we will isolate the 2-thio-2'-O-methyluridine from the sample.
3. Mass Spectrometry Analysis: We will utilize our cutting-edge mass spectrometry facility to accurately measure the level of 2-thio-2'-O-methyluridine.
4. Data Analysis: Our bioinformatics team will perform comprehensive data analysis, including statistical analysis and pathway analysis.
5. Report Delivery: We will deliver a detailed report that includes an overview of the methods used, the results obtained, and their interpretation.
Service Advantages
Applications
Our 2-thio-2'-O-methyluridine analysis service can be applied in various areas including:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 2-thio-2'-O-methyluridine
4. Raw Data
5. Custom Analysis Report
For more information about our 2-thio-2'-O-methyluridine analysis service or any of our other services, please do not hesitate to contact us. At MtoZ Biolabs, we are dedicated to providing our customers with top-quality services.
How to order?
