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    3-Aminosalicylic Acid Analysis Service

      3-Aminosalicylic acid (3-ASA) is an organic compound belonging to the salicylic acid family, characterized by the presence of an amino group (-NH₂) at the third position of the benzene ring and a carboxylic acid group (-COOH) at the first position. This unique structure allows 3-aminosalicylic acid to interact with various molecular targets, contributing to its anti-inflammatory and antimicrobial properties, which are particularly relevant in the treatment of certain bacterial infections, such as tuberculosis. In the body, 3-aminosalicylic acid is primarily metabolized in the liver, where it undergoes processes like acetylation and conjugation with glucuronic acid to form more water-soluble metabolites, which are subsequently excreted in the urine. The metabolism of 3-ASA can affect its therapeutic efficacy and safety profile, influencing its absorption, distribution, and elimination.

       

      Metabolomics analysis of 3-aminosalicylic acid utilizes high-throughput techniques such as mass spectrometry and nuclear magnetic resonance to comprehensively study its dynamic changes and metabolic pathways within the body. This analytical approach is crucial for elucidating the biological functions of 3-aminosalicylic acid, optimizing its clinical applications in treating inflammatory and infectious diseases, evaluating the impact of its excess or abnormal metabolism on health, and advancing personalized medical interventions.

       

      1831212888326000640-TheStructureof3-AminosalicylicAcid.png

      Figure 1. The Structure of 3-Aminosalicylic Acid

       

      MtoZ Biolabs is proud to present our state-of-the-art 3-Aminosalicylic Acid Analysis Service. This service is built upon our pioneering liquid chromatography-mass spectrometry (LC-MS) platform, and is run by our team of metabolomics experts. We offer an all-inclusive 3-aminosalicylic acid analysis, guaranteeing high sensitivity and precision.

       

      Analysis Workflow

       

      1831212961407553536-Workflowof3-AminosalicylicAcidAnalysisService.PNG

       

      Service Advantages

      1. High quality data: We deliver reliable and reproducible results with our advanced LC-MS system.

       

      2. Expertise: Our experienced team of scientists ensures the quality and accuracy of our analysis.

       

      3. Comprehensive report: We provide a detailed report including the experimental procedure, instrument parameters, and results interpretation.

       

      4. Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

       

      Applications

      • Qualitative analysis of 3-aminosalicylic acid metabolites.
      • Quantitative evaluation of 3-aminosalicylic acid content.
      • Providing data for potential improvements in 3-aminosalicylic acid usage.

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. A minimum of 3 samples exhibiting similar conditions must be selected for each analysis.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Samples should be stored at -80°C to ensure stability.

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedure

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 3-Aminosalicylic Acid

      4. Raw Data

      5. Custom Analysis Report

       

      Our 3-aminosalicylic acid analysis service is designed to simplify your research and product development by delivering accurate and reliable data.

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