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    5-formyl-2'-deoxycytidine Analysis Service

      5-formyl-2'-deoxycytidine (5fdC) is a DNA pyrimidine nucleoside. It is the oxidized derivative of 5-methyl-2'-deoxycytidine and is produced through a complex metabolic process involving TET enzymes. The modification and oxidation of the methyl group on 5-methyl-2'-deoxycytidine turn it into 5fdC. 5fdC plays a crucial role in the field of molecular biology and genetics. It is one of the vehicles of active DNA demethylation and is involved in the regulation of gene expression. Moreover, it is a key component in the studies related to DNA damage, repair, and replication. Given the importance of 5fdC in genetic and molecular biology studies, the accurate quantification and characterization of this compound are crucial. It can help in identifying the role it plays in various cellular processes and the implications of its alterations in diseases like cancer.

       

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      Figure 1. The Structure of 5-formyl-2'-deoxycytidine

       

      At MtoZ Biolabs, we have developed a comprehensive 5-formyl-2'-deoxycytidine analysis service using advanced mass spectrometry techniques. Our service aims to provide accurate and reliable quantification of 5fdC in various biological samples, and to offer insights into its metabolic pathway.

       

      Analysis Workflow

       

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      Service Advantages

      • Advanced mass spectrometry techniques for accurate and reliable results.
      • Expert team with extensive knowledge and experience in metabolomics analysis.
      • Comprehensive report with detailed data interpretation and recommendations.
      • Strict data confidentiality and secure sample storage.

       

      Applications

      Our 5fdC analysis service is applicable in:

      • Molecular biology research.
      • Genetic studies.
      • Disease research, especially in cancer.

       

      Sample Submission Requirements

       

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      • Samples should be stored at -80℃ and shipped with dry ice.
      • It is necessary to prepare more than 3 biological replicates for each type of sample.
      • Please provide details on sample collection and handling.
      • Other sample types, please contact us for more details.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on 5-formyl-2'-deoxycytidine

      4. Raw Data

      5. Custom Analysis Report

       

      MtoZ Biolabs is committed to providing top-notch metabolomics services to meet your research needs. With our advanced technology and dedicated team, we ensure accurate and reliable results for your 5fdC analysis. Contact us today to learn more about our services.

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