5-Hydroxyindole-3-Acetic Acid Analysis Service
- State-of-the-art HPLC-MS/MS systems
- Highly experienced analytical team
- Rigorous data analysis and quality control
- Comprehensive report with both raw data, processed data and interpretation of the results
- Competitive pricing and fast turnaround time
- Studying the pathology of serotonin-related disorders.
- Diagnosing and monitoring carcinoid tumors.
- Investigating the role of 5-HIAA in various biological phenomena.
- Samples should be stored at -80℃ and shipped with dry ice.
- We recommend providing at least 3 samples of similar conditions for each type of sample.
- Please provide details on sample collection and handling.
- Other sample types, please contact us for more details.
5-Hydroxyindole-3-acetic acid (5-HIAA) is a key metabolite of serotonin, a neurotransmitter critical for regulating mood, sleep, and gastrointestinal function. Chemically, 5-HIAA is an indoleacetic acid derivative characterized by its structure comprising a hydroxyl group on the indole ring and an acetic acid side chain.
Figure 1. The Structure of 5-Hydroxyindole-3-Acetic Acid
5-HIAA is primarily synthesized in the liver from serotonin through oxidative metabolism. Its concentration in biological fluids, particularly in urine, reflects the systemic levels of serotonin, making it an important biomarker for assessing serotonergic activity. Elevated or decreased levels of 5-HIAA are associated with various clinical conditions, including serotonin-producing tumors (such as carcinoid tumors), psychiatric disorders, and gastrointestinal diseases.
The analysis of 5-HIAA is crucial for diagnosing and monitoring conditions related to altered serotonin metabolism. For instance, increased 5-HIAA levels can indicate the presence of neuroendocrine tumors or carcinoid syndrome, while decreased levels may be indicative of serotonin deficiency or other metabolic disorders. Accurate measurement of 5-HIAA provides essential information for patient management and therapeutic interventions.
At MtoZ Biolabs, we offer comprehensive 5-Hydroxyindole-3-Acetic Acid Analysis Services utilizing high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) techniques. Our expertise ensures precise quantification and reliable results, supporting clinical diagnostics and research applications with the highest level of accuracy and professionalism.
Analysis Workflow
Service Advantages
Applications
Our 5-HIAA Analysis Service can be used for various applications including:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 5-Hydroxyindole-3-Acetic Acid
4. Raw Data
5. Custom Analysis Report
Please feel free to contact us if you have any further queries. Our team is always ready to provide personalized service to meet your research needs.
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