5-Hydroxytryptophan Analysis Service

5-Hydroxytryptophan (5-HTP) is a naturally occurring amino acid and a chemical precursor in the biosynthesis of the neurotransmitters serotonin and melatonin. It is derived from the seeds of an African plant, Griffonia simplicifolia, and is widely used in the pharmaceutical and dietary supplement industries due to its potential health benefits.

 

Serotonin, a neurotransmitter synthesized from 5-HTP, plays a crucial role in the regulation of mood, anxiety, sleep, and appetite. Imbalance in serotonin levels is linked to various mental disorders including depression and anxiety. Hence, 5-HTP as the direct precursor of serotonin, is of significant interest in neuropsychiatric research.

 

Given the crucial role of 5-HTP in human health and disease, precise and comprehensive analysis of 5-HTP is essential in various research fields including pharmacology, neurology, and nutrition. Its analysis can assist in understanding the complex metabolic pathways and mechanisms underlying various health conditions and neuropsychiatric disorders.

 



 

Liu, X. X. et al. Front Bioeng Biotechnol. 2021.

 

Figure 1. The 5-HTP Metabolic Pathway and Its Function

 

At MtoZ Biolabs, we offer a comprehensive 5-Hydroxytryptophan analysis service, using our advanced LC-MS/MS systems and the expertise of our team of skilled scientists. Our service helps to accurately quantify 5-HTP in different types of samples, aiding researchers in understanding the role and significance of this important metabolite in various biological processes.

 

Analysis Workflow

 



 

Service Advantages

• High sensitivity and accuracy: Our advanced LC-MS/MS systems ensure high sensitivity and accuracy in the quantification of 5-HTP.
• Wide applicability: We accept a wide range of sample types, including plasma, tissue, cells, and food products.
• Experienced team: Our team of skilled scientists can provide expert guidance and technical support throughout the process.
• Fast turnaround: The process from sample handling to report generation is efficient, shortening the analysis cycle.

 

Applications

Our 5-HTP analysis service can be applied in:

• Studying the metabolic pathways of 5-HTP
• Investigating the role of 5-HTP in various health conditions and diseases
• Evaluating the effectiveness of dietary supplements or drugs that influence 5-HTP levels

 

Sample Submission Requirements

 



 

• Samples should be stored at -80℃ and shipped with dry ice.
• We recommend providing at least 3 samples of similar conditions for each type of sample.
• Please provide details on sample collection and handling.
• Other sample types, please contact us for more details.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on 5-Hydroxytryptophan

4. Raw Data

5. Custom Analysis Report

 

For more information about our 5-HTP analysis service, please contact us.