5-hydroxyuridine Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Biomarker discovery
- Disease diagnosis and prognosis
- Drug response prediction
- Basic biological research
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
5-hydroxyuridine (ho5U) is a modified nucleoside that originates from RNA molecules. Structurally, it consists of a uracil base attached to a ribose sugar with an additional hydroxyl group at the 5th position of the uracil ring. The metabolic process of ho5U involves multiple enzymes, including kinases and hydrolases, that add or remove phosphate groups for its conversion. ho5U is involved in various biological processes, such as RNA metabolism, gene expression regulation, and cellular response to stress. It has been implicated in numerous diseases including cancer, neurodegenerative disorders, and autoimmune diseases, making it a potentially significant biomarker. Understanding the alterations in the levels of ho5U could provide crucial insights into disease mechanisms and can potentially lead to the development of diagnostic tools and therapeutic strategies. Therefore, accurate and sensitive analysis of 5-hydroxyuridine is indispensable in biomedical research.
Figure 1. The Structure of 5-hydroxyuridine
MtoZ Biolabs is an industry-leading company providing comprehensive metabolomics services, including our specialized 5-hydroxyuridine analysis service. We are equipped with cutting-edge techniques and a team of experienced scientists for accurate analysis of 5-hydroxyuridine in various sample types.
Analysis Workflow
At MtoZ Biolabs, we use LC-MS/MS (Liquid Chromatography-Tandem Mass Spectrometry) for 5-hydroxyuridine analysis, providing a detailed and reliable assessment of ho5U level in your samples. Our service includes: Sample Preparation, Metabolite Extraction, Mass Spectrometry, Data Processing, Bioinformatics Analysis, and Report Generation.
Service Advantages
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Comprehensive Information on 5-hydroxyuridine
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we strive to provide you with the most reliable and accurate 5-hydroxyuridine analysis service to expedite your research. Contact us today to discuss your project requirements.
How to order?
