5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic Acid Analysis Service
- Quantify 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid in different biological samples
- Uncover its potential roles in various biological processes
- Identify possible associations between this metabolite and various diseases
- Investigate inflammatory pathway regulation in biological samples.
- Identify potential biomarkers for disease diagnostics.
- Quantify lipid mediators in metabolic disorders.
- Monitor treatment response in inflammatory diseases.
- Analyze lipid profiles in cardiovascular disease studies.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid is a specialized lipid mediator derived from arachidonic acid, known for its involvement in complex inflammatory and immune processes. This compound features hydroxyl groups at the 5S and 12R positions and a dioic acid functional group, giving it distinct biochemical properties that make it essential in the regulation of inflammation. The conjugated tetraene system also contributes to its reactivity, particularly in pathways related to leukotriene metabolism.
This metabolite is a downstream product of the lipoxygenase pathway, where it is formed through the enzymatic oxidation of arachidonic acid. Its role has been highlighted in studies exploring the regulation of immune responses, particularly in respiratory inflammation, cardiovascular diseases, and certain cancers. As part of the broader class of eicosanoids, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid is crucial for modulating immune cell recruitment, vascular permeability, and smooth muscle contraction, making it a target of interest in pharmacological research aimed at developing anti-inflammatory and immunomodulatory therapies.
Figure 1. The Structure of 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic Acid
The accurate quantification of this metabolite is essential for understanding its involvement in pathological processes and for developing therapeutic strategies targeting eicosanoid pathways. Research into 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid helps advance our understanding of lipid signaling and its broader implications in disease progression.
MtoZ Biolabs utilizes advanced mass spectrometry instruments coupled with professional metabolomics data analysis pipelines to provide accurate and reliable analysis of 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid. Specifically, we can help you:
Analysis Workflow
Service Advantages
1. Advance Analysis Platform
MtoZ Biolabs established an advanced 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid analysis service platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge
Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality
Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid analysis service data providing clients with a comprehensive data report.
4. Fast Turnaround
The process from sample handling to report generation is efficient, shortening the analysis cycle.
Applications
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Comprehensive Experimental details (Materials, Instruments, and Methods, etc.)
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic Acid
4. Raw Data
5. Custom Analysis Report
Join our growing network of satisfied customers and discover how MtoZ Biolabs can enhance your research. Contact us today to learn more about our 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraene-1,20-dioic acid analysis service.
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