Amino Acid

Amino acids are the fundamental building blocks of proteins and play numerous crucial roles in biological systems. Beyond being the constituents of proteins, amino acids are involved in metabolic regulation, signal transduction, immune function, and energy supply. Amino acid metabolism refers to the synthesis, breakdown, and transformation of amino acids within organisms. These processes not only maintain normal bodily functions but also play critical roles in stress responses and disease states. Changes in amino acid levels can indicate an organism's nutritional status, metabolic conditions, and responses to environmental factors. Abnormal levels of amino acids are linked to various diseases, including metabolic disorders, cardiovascular diseases, and neurodegenerative disorders. Hence, precise amino acid analysis is essential for elucidating biological mechanisms, diagnosing diseases, and assessing nutritional status.

 

 

Figure 1. Structure of a Typical L-α-Amino Acid

 

MtoZ Biolabs offers specialized amino acid analysis services, combining advanced ultra-high-performance liquid chromatography (UHPLC) and mass spectrometry (MS) techniques to provide clients with accurate and reliable quantitative analysis of amino acids, supporting scientific research and applications.

 

Analysis Workflow

 



 

Service Advantages

 



 

Sample Submission Requirements

Sample Types

Serum, plasma, urine, tissue homogenates, and other biological samples.

 

Sample Volume

At least 200 μL of liquid sample or 200 mg of tissue sample.

 

Sample Preservation

Store and transport samples at -80°C to maintain amino acid stability.

 

Applications

Disease Mechanism Research: Investigate the molecular mechanisms of metabolic disorders, cardiovascular diseases, and neurodegenerative diseases through amino acid analysis.

 

Biomarker Discovery: Identify and validate amino acids as potential disease biomarkers.

 

Nutrition and Metabolism Research: Assess the impact of nutritional interventions on amino acid metabolism, revealing their role in energy metabolism.

 

Drug Development: Evaluate the effects of drugs on amino acid metabolism, supporting drug screening and target validation.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Amino Acids

4. Raw Data

5. Custom Analysis Report