Amino Acids and Their Derivatives Analysis Service

Amino acids are biologically important organic compounds, composed of amine (-NH₂) and carboxylic acid (-COOH) functional groups, along with a side chain attached to each amino acid. Amino acid analysis is a fundamental tool in the analysis of proteins, peptides, and other amino acid-based drugs. Amino acid analysis allows for the quantitative and qualitative analysis of the amino acid composition of samples and enables the determination of atypical amino acids that may be present in proteins and peptides

 



Tsun, Z. et al. Semin. Cell Dev. Biol. 2015.

Figure 1. Demonstration of Important Biological Functions of Amino Acids


MtoZ Biolabs utilizes both GC/MS (Agilent 7890A/5975C) and LC/MS/MS (AB Sciex 5500) platforms. This allows for the quantitative and qualitative analysis of over 70 types of amino acids and their derivatives, with 95% of the substances involving standard and isotopic standards for quantification.

 

Services at MtoZ Biolabs

The technicians at MtoZ Biolabs, through many years of technical accumulation, use both GC/MS (Agilent 7890A/5975C) and LC/MS/MS (AB Sciex 5500) platforms. This achieves quantitative and qualitative analysis of over 70 types of amino acids and their derivatives:

 



Figure 2. MtoZ Biolabs can Detect Amino Acids and their Derivatives

 

Sample Submission Requirements

1. Sample Type and Volume



For other sample types and amounts, please contact MtoZ Biolabs.

 

2. Sample Transportation

Calculate with 3-4 kg of dry ice evaporating per day, please use a sufficient amount of dry ice for transportation (it is recommended to use larger pieces of dry ice, as larger pieces evaporate more slowly), and seal with a foam box. Also, try to choose a faster mailing method to reduce the possibility of sample degradation during transportation.

 

Applications

1. Plant Research

Reveals metabolic mechanisms related to plant growth, stress tolerance, and aging, aiding in understanding environmental adaptations.

 

2. Human Health Research

Supports the diagnosis and treatment monitoring of diseases like cardiovascular conditions, diabetes, and cancer by analyzing amino acid metabolism.

 

3. Neuroscience Research

Helps study neurotransmitter-related amino acids, providing insights into neurological diseases like depression and Parkinson’s.

 

4. Food and Nutrition Science

Quantifies amino acids in food, assessing nutritional content and studying their effects on human health. 

 

Deliverables

In the technical report, MtoZ Biolabs will provide you with detailed technical information, including:

1. Experimental Procedures

2. Relevant Mass Spectrometry Parameters

3. Information on the Qualitative or Quantitative Characterization of the Substance

4. Mass Spectrometry Images

5. Raw Data