Bradykinin Analysis Service
- Extensive expertise in handling various biological samples and extracting metabolites.
- State-of-the-art mass spectrometry platforms.
- Strict quality control to ensure reliable results.
- Comprehensive statistical and bioinformatics analysis.
- Personalized service to meet various research needs.
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Bradykinin is a short peptide composed of nine amino acid residues, with the sequence Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg. It is generated from kininogen through the action of kallikrein. The kinin system consists of high-molecular-weight kininogen (HMWK) and low-molecular-weight kininogen (LMWK), with bradykinin primarily produced from HMWK. Bradykinin exhibits various biological activities and plays a crucial role in multiple physiological and pathological processes, particularly in vasodilation, blood pressure regulation, inflammatory responses, and pain perception. In chronic inflammatory diseases such as rheumatoid arthritis and systemic lupus erythematosus, elevated levels of bradykinin can serve as an indicator of disease activity. The role of bradykinin in pain perception has been extensively studied. By analyzing bradykinin and its metabolites, one can gain a deeper understanding of the biological mechanisms of pain and provide new therapeutic strategies for pain management.
Figure 1. The Structure of Bradykinin
MtoZ Biolabs provides a premium Bradykinin Analysis Service, supported by our state-of-the-art liquid chromatography-mass spectrometry (LC-MS) platform and expert metabolomics team. Our comprehensive bradykinin analysis ensures sensitivity and precision of the highest degree, helping to understand the role of bradykinin in physiological and pathological processes and advancing research into related diseases.
Analysis Workflow
Service Advantages
Applications
1. Discovering novel disease biomarkers
2. Improving disease diagnostic procedures
3. Accelerating the discovery of innovative therapeutic strategies
4. Yielding new insights into disease mechanisms
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. A minimum of 3 materials under the same conditions must be selected for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to ensure stability.
Note: Provide specific information on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Bradykinin
4. Raw Data
5. Custom Analysis Report
Our Bradykinin Analysis Service is designed to expedite your research and product development by offering accurate and reliable data.
How to order?
