Chenodeoxycholic Acid 24-Acyl-Beta-D-Glucuronide Analysis Service

Chenodeoxycholic acid 24-acyl-beta-D-glucuronide is a bile acid glucuronide derivative formed by the conjugation of chenodeoxycholic acid (CDCA) with glucuronic acid at the 24th carbon position. As a conjugate of bile acid, it plays an important role in the metabolism and excretion of bile acids, enhancing their solubility and facilitating their excretion via the biliary system. The conjugated form of chenodeoxycholic acid 24-acyl-beta-D-glucuronide is significant in hepatic detoxification pathways because it is less cytotoxic than the unconjugated form. In the context of liver function, this glucuronidation is a mechanism to protect cells from damage caused by the accumulation of bile acids. High-performance liquid chromatography (HPLC) can separate and quantify the glucuronide in complex biological matrices. Mass spectrometry can identify and quantify chenodeoxycholic acid 24-acyl-beta-D-glucuronide in biological samples. These analytical methods can help researchers better understand the functions and mechanisms of chenodeoxycholic acid 24-acyl-beta-D-glucuronide.

 



Figure 1. The Structure of Chenodeoxycholic Acid 24-Acyl-Beta-D-Glucuronide

 

At MtoZ Biolabs, we offer a well-developed Chenodeoxycholic Acid 24-Acyl-Beta-D-Glucuronide Analysis Service, supported by our advanced liquid chromatography-mass spectrometry (LC-MS) platform and experienced metabolomics team. Our service guarantees a comprehensive analysis of this compound, providing high sensitivity and accuracy in all results.

 

Analysis Workflow 

 



 

Service Advantages

1. Continuously optimized experimental protocols and advanced instrument

 

2. Professional experimental design

 

3. Rapid turnaround time

 

4. High accuracy, specificity, and sensitivity

 

Applications

• Qualitative and quantitative analysis of chenodeoxycholic acid 24-acyl-beta-D-glucuronide
• Study of metabolites derived from this compound
• Support for drug development and disease research

 

Sample Submission Requirements

1. Sample Types

Serum, plasma, urine, tissues, and other biological samples are accepted. At least three samples under the same condition are required for each test. 

 

2. Sample Volume

• Animal tissue ≥ 50 mg
• Plant tissue ≥ 100 mg
• Serum/ Plasma ≥ 100 μL
• Urine ≥ 1 mL

 

3. Sample Preservation

Samples should be stored at -80°C to maintain stability.

 

Note: Please provide details on sample collection and handling.

 

Deliverables

1. Experimental Procedures

2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

3. Detailed Information on Chenodeoxycholic Acid 24-Acyl-Beta-D-Glucuronide

4. Raw Data

5. Custom Analysis Report

 

With our Chenodeoxycholic Acid 24-Acyl-Beta-D-Glucuronide Analysis Service, we aspire to accelerate your research and drug development processes by providing accurate, reliable, and comprehensive metabolic data.