Diphtheria Toxin Analysis Service
- Sample Type: Serum, plasma, tissue, or cell culture
- Sample Volume: Minimum 100 μL for serum/plasma, 200 mg for solid tissue, or 1x10⁷ cells for cell culture
Diphtheria toxin is a single, approximately 58,000 daltons, polypeptide chain. It is the primary virulent factor produced by Corynebacterium diphtheriae and related species, causing the disease diphtheria. The toxin gains entry into the cytoplasm of susceptible cells by binding to the cell's surface, and it inhibits protein synthesis by inactivating elongation factor-2. MtoZ Biolabs provides a comprehensive Diphtheria Toxin Analysis Service utilizing cutting-edge Mass Spectrometry technologies.
Figure 1. Diphtheria Toxin Precursor
Analysis Workflow
The identification and quantification of Diphtheria Toxin are done through Liquid Chromatography-Mass Spectrometry (LC-MS). This technique combines the physical separation capabilities of liquid chromatography with the mass analysis capabilities of mass spectrometry. It has become an essential analytical technique for the detection and characterization of Diphtheria Toxin.
Applications
Our Diphtheria Toxin Analysis Service can be applied in various fields like disease research, drug development, environmental science, and food safety. It is especially crucial in monitoring the presence and level of Diphtheria Toxin in samples, which can greatly aid in the prevention and treatment of diphtheria.
Sample Submission Requirements
For specific sample submission requirements, please contact our customer service team.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Diphtheria Toxin Analysis
4. Raw Data
5. Custom Analysis Report
For more details about our Diphtheria Toxin Analysis Service, please feel free to contact us. Our dedicated team is ready to provide you with a customized analysis plan to meet your research needs.
How to order?
