Dopa Analysis Service
- Expert team: Our team has extensive experience in metabolomics and mass spectrometry.
- Advanced technology: We use the latest technology in mass spectrometry for high sensitivity and accuracy.
- Comprehensive service: From sample preparation to data analysis, we offer a one-stop solution for Dopa analysis.
- Customizable service: We can customize our analysis based on your specific research needs.
- Neurobiology: Understanding the role of Dopa in various brain functions.
- Drug discovery: Analyzing the effect of drugs on Dopa levels.
- Psychiatry: Studying the link between Dopa levels and various mental disorders.
- Samples should be stored at -80℃ and shipped with dry ice.
- We recommend providing at least 3 samples of similar conditions for each type of sample.
- Please provide details on sample collection and handling.
- Other sample types, please contact us for more details.
Dopa, also known as levodopa and l-3,4-dihydroxyphenylalanine, is a vital amino acid derivative with the molecular formula C₉H₁₁NO₄. It plays a critical role in the biosynthesis of catecholamines, including dopamine, norepinephrine, and epinephrine, making it essential for neurological function. Dopa is produced endogenously through the hydroxylation of the amino acid tyrosine, a reaction catalyzed by the enzyme tyrosine hydroxylase. This process is the rate-limiting step in catecholamine biosynthesis, and L-Dopa (levodopa), the biologically active form, is widely used in the treatment of Parkinson’s disease due to its ability to cross the blood-brain barrier and replenish dopamine levels in the brain.
In the dopaminergic pathway, Dopa is decarboxylated by aromatic L-amino acid decarboxylase (AADC) to form dopamine, which can then be converted into norepinephrine and epinephrine. These neurotransmitters play a crucial role in regulating motor control, mood, and autonomic functions. Dopa is also a precursor in the production of melanin, further extending its significance to skin pigmentation.
Research into Dopa metabolism is essential for understanding disorders such as Parkinson’s disease, schizophrenia, and hypertension, as well as conditions related to catecholamine imbalances. Additionally, investigating Dopa and its metabolic intermediates provides valuable insights into the efficacy of therapeutic interventions, particularly for neurodegenerative diseases.
Figure 1. The Structure of Dopa
At MtoZ Biolabs, we offer comprehensive Dopa analysis service to meet your diverse research needs. Our state-of-the-art mass spectrometry platforms, coupled with our expertise in metabolomics, allows us to provide accurate and reliable Dopa analysis. We can help you in determining the levels of Dopa and related metabolites in a wide range of samples, assisting in understanding its role in various biological processes and diseases.
Analysis Workflow
Service Advantages
Applications
Our Dopa analysis service can be applied in various fields including:
Sample Submission Requirements
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Dopa
4. Raw Data
5. Custom Analysis Report
At MtoZ Biolabs, we are committed to providing you with the best quality service to meet your research needs. Contact us today to learn more about our Dopa analysis service.
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