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    Gout Metabolomics Service

      Gout is a complex form of inflammatory arthritis characterized by sudden, severe attacks of pain, redness, and tenderness in joints, most commonly the big toe. The etiology of gout is multifactorial and involves a wide array of metabolic processes. It is primarily caused by the accumulation of urate crystals in the joints, resulting from elevated levels of uric acid in the blood. This hyperuricemia can be due to an overproduction of uric acid or inefficient excretion by the kidneys. While gout has been traditionally associated with lifestyle factors such as diet and alcohol consumption, recent studies have highlighted the importance of genetic predisposition and metabolic dysfunctions in its pathogenesis.

       

      Beyond the classic purine metabolism, other metabolic pathways, including lipid metabolism, oxidative stress, and amino acid metabolism, have been implicated in the disease's progression. By providing a global overview of metabolic changes associated with gout, metabolomics can help in identifying novel biomarkers and potential therapeutic targets, leading to more personalized and effective treatments.

       

      MtoZ Biolabs offer a comprehensive Gout Metabolomics Service, leveraging advanced mass spectrometry technologies and expert bioinformatics analysis. Our service is designed to provide detailed insights into the metabolic alterations associated with gout, supporting research and development efforts in this critical area of healthcare.

       

      Analysis Workflow

       

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      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms: UPLC-MS, LC-MS, GC-MS, MRM method. 
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      • Discover new biomarkers for gout
      • Understand the metabolic pathways involved in gout
      • Investigate the effect of therapeutics on gout
      • Monitor disease progression and treatment response

       

      At MtoZ Biolabs, we are committed to delivering high-quality data and outstanding customer service. Contact us today to discuss how our Gout Metabolomics Service can support your research.

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