How Many Proteins Can Label-Free Detect
Label-free technology is extensively applied in proteomics research for the identification and quantification of proteins within samples. Unlike methods that utilize fluorescent or radioactive labels, this approach employs mass spectrometry (MS) for the direct analysis of proteins. The number of detectable proteins is contingent upon several factors, such as the performance of the mass spectrometer, sample complexity, experimental design, and data processing and analysis techniques. Modern MS technologies are capable of identifying thousands to tens of thousands of distinct proteins. For particularly complex samples, including whole cell lysates or tissue extracts, high-resolution mass spectrometers and optimized experimental protocols can reliably identify thousands of proteins.
MtoZ Biolabs, an integrated chromatography and mass spectrometry (MS) services provider.
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