Hypoxanthine Analysis Service
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
Hypoxanthine is a purine derivative with the chemical formula C₅H₄N₄O. Its structure consists of a purine ring with two nitrogen atoms, along with a hydroxyl group (-OH) and an amino group (-NH₂). As an important intermediate in biological systems, hypoxanthine plays a crucial role in nucleic acid metabolism. Hypoxanthine is primarily derived from the degradation of nucleic acids. In cells, the breakdown of adenine and guanine nucleotides produces hypoxanthine. Additionally, it can be ingested through dietary sources, such as certain meats, fish, and legumes that are rich in purines.
In some plants, the content of hypoxanthine can serve as an indicator of their nutritional value and antioxidant capacity. Certain purine-rich plants, such as legumes and grains, may have higher levels of hypoxanthine. In the body, hypoxanthine is metabolized to generate adenosine monophosphate (AMP) and uric acid. In biological samples from animals or humans, the levels of hypoxanthine and its metabolites can reflect the metabolic state and health status of the organism. For example, elevated uric acid levels may be associated with metabolic disorders or increased disease risk.
Figure 1. The Structure of Hypoxanthine
Mass spectrometry-based metabolomics methods can simultaneously detect and quantify thousands of metabolic features and are widely used for the metabolic analysis of various compounds. MtoZ Biolabs utilizes an LC-MS-based metabolomics research platform for the analysis of hypoxanthine. We ensure the accuracy of the quantification of hypoxanthine and its metabolites, as well as the comprehensiveness and precision of metabolite identification. If you would like to learn more about our hypoxanthine analysis services, please feel free to contact us, and we will be more than happy to assist you.
Analysis Workflow
Service Advantages
1. Experienced: MtoZ Biolabs has a professional research team and advanced technical equipment, capable of providing high-quality services and support to meet the specific needs of clients.
2. Wide Applicability: It is suitable for various types of samples, including plants, animals, and biological fluids, making it applicable across a broad range of fields.
3. High Throughput: Mass spectrometry technology can analyze multiple metabolites simultaneously in a short time, making it suitable for high-throughput analysis of large-scale samples.
4. Targeted Compounds: Targeted metabolomics focuses on specific metabolites, effectively eliminating interference signals and enhancing the reliability of the data.
5. Strong Detection Capability: Mass spectrometry technology can detect low concentrations of metabolites, making it suitable for analyzing rare or complex components in biological samples.
Applications
1. Discovery of novel disease biomarkers
2. Enhancement of disease prognosis
3. Acceleration of innovative therapeutic discovery
4. Unearthing new insights into disease mechanisms
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is necessary to select more than 3 materials with the same condition for each sample.
2. Sample Volume
3. Sample Preservation
Store at -80°C to maintain stability.
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on Hypoxanthine
4. Raw Data
5. Custom Analysis Report
Our Hypoxanthine Analysis Service aims to support your research and product development processes by delivering accurate and reliable results.
How to order?
