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    Leu-Ala Analysis Service

      Leu-Ala is a dipeptide composed of two amino acids: leucine (Leu) and alanine (Ala). In this dipeptide, the carboxyl group of leucine is linked to the amino group of alanine through a peptide bond. Leu-Ala combines the hydrophobic nature of leucine, a branched-chain amino acid, with the simpler, smaller structure of alanine, an amino acid that plays a key role in glucose metabolism and protein synthesis.

       

      The content of Leu-Ala can serve as a potential biomarker for specific physiological and pathological states. In clinical and biochemical research, measuring Leu-Ala levels can help assess muscle metabolism, nutritional status, and protein turnover. Changes in Leu-Ala concentrations may be associated with various conditions, such as muscle wasting, metabolic disorders, and liver function abnormalities, thus offering diagnostic and monitoring value. Leu-Ala can be further metabolized in the body, participating in key metabolic pathways such as branched-chain amino acid catabolism and alanine-glucose cycle. These pathways are essential for maintaining energy balance, regulating glucose levels, and supporting protein metabolism. Analysis of Leu-Ala and its metabolites can reveal its specific functions and mechanisms in muscle health, energy production, and metabolic regulation.

       

      1834436340742737920-TheStructureofLeu-Ala.png

      Figure 1. The Structure of Leu-Ala

       

      MtoZ Biolabs offers the cutting-edge Leu-Ala Analysis Service leveraging our advanced liquid chromatography-mass spectrometry (LC-MS) platform and expert metabolomics team. Our service provides comprehensive data on Leu-Ala to meet researchers' needs.

       

      Analysis Workflow 

       

      1834436376750837760-WorkflowofLeu-AlaAnalysisService.PNG

       

      Service Advantages

      • Extensive expertise in handling various biological samples and extracting metabolites.
      • State-of-the-art mass spectrometry platforms.
      • Strict quality control to ensure reliable results.
      • Comprehensive statistical and bioinformatics analysis.
      • Personalized service to meet various research needs.

       

      Applications

      1. Identifying new disease biomarkers

       

      2. Improving disease diagnosis

       

      3. Accelerating the discovery of innovative therapeutics

       

      4. Uncovering new insights into disease mechanisms

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues and other biological samples. For each sample, it is necessary to select more than 3 materials with the same condition. 

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store samples at -80°C to maintain stability.

       

      Note: Please provide details on sample collection and handling. 

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Leu-Ala

      4. Raw Data

      5. Custom Analysis Report

       

      With our Leu-Ala analysis service, we are committed to facilitating your research and product development by providing accurate, reliable results. Trust MtoZ Biolabs for all your metabolomics analysis needs.

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