Metabolomics Analysis

• • Licochalcone C Analysis Service

  Licochalcone C is a natural phenolic compound found primarily in licorice plants. It exhibits a range of potential therapeutic properties, including anti-inflammatory, anti-cancer, and antioxidant activities. Licochalcone C analysis is pivotal to the pharmaceutical and biotechnology industries for the development of natural product-based therapeutics and health supplements.

• • 2-phosphoglycerate Analysis Service

  2-phosphoglycerate, a glyceric acid derivative, is a vital intermediate in several crucial metabolic pathways, including glycolysis, the pentose phosphate pathway, and the Calvin cycle. Investigating how 2-phosphoglycerate influences metabolic alterations in tumor cells and its role in stimulating erythropoietin (EPO) production can enhance our understanding of its regulatory functions.

• • Erythrose-4-phosphate Analysis Service

  Erythrose 4-phosphate is a phosphate of the simple sugar erythrose. It is a key metabolite in several vital metabolic pathways, including the pentose phosphate pathway and the shikimate pathway. A detailed understanding of the Erythrose-4-phosphate metabolism is crucial for the study of various biological processes and diseases.

• • Acetyl-CoA Analysis Service

  Acetyl-CoA, an essential metabolite involved in various biochemical processes, plays pivotal roles in the Krebs cycle, fatty acid metabolism, and protein acetylation. Misregulation of acetyl-CoA metabolism has been linked to numerous diseases, including cancer and neurodegenerative diseases. Despite its importance, the quantification and characterization of acetyl-CoA presents significant challenges due to its high reactivity and instability.

• • Fructose-6-phosphate Analysis Service

  Fructose-6-phosphate (F6P) serves as a crucial intermediary in both glycolysis and gluconeogenesis, processes central to the cellular metabolism of glucose. During glycolysis, under the enzyme phosphofructokinase-1 (PFK-1), F6P is transformed into fructose-1,6-bisphosphate (FBP), a reaction that contributes to a pathway culminating in the generation of ATP and pyruvate. In the pathway of gluconeogenesis, F6P plays a vital role in the synthesis of glucose-6-phosphate...

• • NAD⁺ Precursor (NMNs) Analysis

  Nicotinamide mononucleotide (NMN) is a nucleotide derived from ribose, nicotinamide, its nucleosides, and niacin, and it serves as a crucial precursor to NAD⁺ biosynthesis. NAD⁺ acts as a cofactor in numerous critical cellular processes. Research suggests that increasing NAD⁺ levels may support mitochondrial functions, potentially mitigating aspects of cellular aging.

• • Adenosine Monophosphate Analysis Service

  Adenosine monophosphate (AMP) is a nucleotide that plays a critical role in cellular metabolism and energy transfer. AMP consists of a phosphate group, the sugar ribose, and the nucleobase adenine. AMP's role as a regulatory molecule in energy metabolism makes it crucial for understanding how cells respond to changes in their energy state and how they regulate processes such as glucose uptake, lipid oxidation, and overall energy balance.

• • Adenosine Diphosphate Analysis Service

  Adenosine diphosphate (ADP) plays a pivotal role in cellular energy metabolism as the precursor to adenosine triphosphate (ATP), the cell's primary energy carrier. ATP hydrolyzes into ADP and inorganic phosphate (Pi), releasing energy that supports vital biological processes. The re-phosphorylation of ADP to ATP mainly occurs through mitochondrial oxidative phosphorylation. Additionally, enzymes like creatine kinase facilitate ADP's rapid conversion back to ATP, essential for energy replenishment.

• • α-ketoglutaric Acid Analysis Service

  α-ketoglutaric acid (α-KG), also known as 2-oxoglutaric acid, plays a crucial role in numerous biochemical processes. It is a key intermediate in the Krebs cycle, the body's main process for producing energy and reducing power in cells. Besides, it also plays a pivotal role in amino acid metabolism, neurotransmitter synthesis, and detoxification processes. Therefore, the accurate detection and quantification of α-KG is of great importance in medical and biological research.

• • Fructose 1,6-bisphosphate Analysis Service

  Fructose 1,6-bisphosphate (F1,6BP) is a key metabolic intermediate in both the glycolysis and gluconeogenesis pathways. It functions as a coenzyme in the reversible conversion of glyceraldehyde 3-phosphate and dihydroxyacetone phosphate in triose phosphate isomerase reaction. Understanding the levels and functions of F1,6BP is crucial in the research of metabolic diseases, cancer, and other health-related fields.