Metabolomics Analysis

• • Metanephrine Analysis Service

  Metanephrine is a metabolite formed from epinephrine (also known as adrenaline) through methylation. Epinephrine is a key catecholamine hormone and neurotransmitter that plays a crucial role in regulating blood pressure, heart rate, metabolism, and the body's stress response. Metanephrine is the methylated product of epinephrine, characterized by the addition of a methyl group to the structure of epinephrine. Metanephrine is commonly found in biological systems as an important intermediate product of epinep

• • L-Palmitoylcarnitine Analysis Service

  L-Palmitoylcarnitine is an ester compound formed by the combination of palmitic acid and L-carnitine. L-carnitine is a naturally occurring quaternary ammonium compound that plays a key role in transporting fatty acids into the mitochondria for β-oxidation. L-palmitoylcarnitine is a long-chain acyl derivative of L-carnitine, characterized by the attachment of a palmitoyl group (a 16-carbon saturated fatty acid chain). This molecule is commonly found in biological systems as part of long-chain fatty acid meta

• • 17β-Estradiol Analysis Service

  17β-Estradiol is the most potent and active form of estrogen steroid hormone in humans, playing a crucial role in regulating the reproductive system and the development of secondary sexual characteristics. It is characterized by a hydroxyl group in the β-configuration at the C17 position, which contributes to its high estrogenic activity. 17β-Estradiol is primarily produced in the ovaries, but it is also synthesized in smaller amounts by other tissues, such as the adrenal glands and adipose tissue. Due to i

• • 17α-Estradiol Analysis Service

  17α-Estradiol is a naturally occurring stereoisomer of estradiol, a potent estrogen steroid hormone that plays a role in regulating the reproductive system and the development of secondary sexual characteristics. Unlike 17β-estradiol, which is the most active form of estrogen in humans, 17α-estradiol has weaker estrogenic activity and is characterized by a hydroxyl group in the α-configuration at the C17 position. 

• • Calcifediol Analysis Service

  Calcifediol is the primary hydroxylated metabolite of vitamin D, characterized by the presence of a hydroxyl (–OH) group at the 25th carbon position of the cholesterol molecule. Calcifediol is formed in the liver from cholesterol-derived vitamin D (such as vitamin D3 or D2) through the catalytic action of 25-hydroxylase (CYP2R1) and serves as an important endogenous marker in biological systems, reflecting the body's vitamin D status. Calcifediol exhibits significant biological activity in the body, particu

• • 5'-Deoxy-5'-methylthioadensine Analysis Service

  5'-Deoxy-5'-methylthioadenosine (MTA) is a sulfur-containing nucleoside derivative characterized by a methylthio group (–SCH₃) attached to the 5' carbon of the ribose sugar in the adenosine molecule. It is a byproduct of polyamine biosynthesis, produced through the enzymatic conversion of S-adenosylmethionine (SAM) by S-adenosylmethionine decarboxylase (SAMDC) and subsequent reactions. MTA is found in various tissues and cells where it plays important roles in cellular metabolism and signal transduction.

• • 20α-Hydroxycholesterol Analysis Service

  20α-Hydroxycholesterol (20α-OHC) is a hydroxylated derivative of cholesterol, characterized by the presence of a hydroxyl (–OH) group at the 20th carbon position of the sterol backbone. It belongs to the oxysterol class, which are oxidized derivatives of cholesterol, and is produced through enzymatic processes involving cholesterol hydroxylases, such as cytochrome P450 enzymes, specifically CYP11A1, also known as cholesterol side-chain cleavage enzyme. 20α-OHC is primarily synthesized in steroidogenic tissu

• • N-Formylkynurenine Analysis Service

  N-Formylkynurenine is a formylated derivative of kynurenine, an intermediate in the tryptophan catabolism pathway. Its structure consists of a kynurenine core with a formyl group attached to the amino group at the N-position. This compound is primarily known for its role as a precursor in the kynurenine pathway, the main route of tryptophan degradation in mammals. N-Formylkynurenine is formed from tryptophan by the action of the enzyme indoleamine 2,3-dioxygenase (IDO) or tryptophan 2,3-dioxygenase (TDO), b

• • 1-Methylxanthine Analysis Service

  1-Methylxanthine is a methylated derivative of xanthine, a purine base found in most human tissues and other organisms. Its structure consists of a xanthine core with a methyl group attached to the nitrogen at the 1-position of the imidazole ring. This class of compounds is known for its stimulatory effects on the central nervous system and its ability to act as adenosine receptor antagonists. 1-Methylxanthine is a metabolic product in the caffeine metabolism process, formed by the enzyme cytochrome P450 1A

• • Paraxanthine Analysis Service

  Paraxanthine (1,7-dimethylxanthine) is a primary metabolite of caffeine, produced in the body by the demethylation of caffeine by cytochrome P450 1A2 (CYP1A2) enzyme. Its structure is characterized by a xanthine core with methyl groups attached at the 1 and 7 positions. Paraxanthine is further metabolized in the body by enzymes such as xanthine oxidase and N-acetyltransferase, which convert it into various other metabolites like 1-methylxanthine and 1-methyluric acid. paraxanthine has a relatively short hal