Metabolomics Analysis
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• 5-hydroxymethyluridine Analysis Service
5-hydroxymethyluridine (5hmU) is a part of RNA modifications, originating from the methylation of uridine at the 5th carbon position. The structure of 5hmU includes a uracil ring, with a hydroxymethyl group at the 5th carbon position, giving it unique chemical properties among RNA modifications. 5-hydroxymethyluridine has applications in various biological processes, such as gene expression regulation, RNA stability, and response to stress.
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• N6-(cis-hydroxyisopentenyl)adenosine Analysis Service
N6-(cis-hydroxyisopentenyl)adenosine (or io6A in short) is a modified nucleoside that is found in the transfer RNA (tRNA) of both eukaryotes and prokaryotes. It plays a key role in the regulation of protein translation. Structurally, io6A is characterized by the addition of a cis-hydroxyisopentenyl group to the N6 position of adenosine. This modification occurs post-transcriptionally and is essential for maintaining the accuracy and efficiency of codon recognition during protein synthesis.
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• N6-acetyladenosine Analysis Service
N6-acetyladenosine is a modified nucleoside found in tRNA and other RNA molecules. It is derived from adenosine, a nucleoside that forms an important part of DNA and RNA. Structurally, N6-acetyladenosine is characterized by an acetyl group attached to the nitrogen atom at the 6th position of the adenosine molecule. The metabolism of N6-acetyladenosine is largely unknown, but it is thought to be involved in the regulation of gene expression and protein synthesis.
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• N4-acetyl-2'-O-methylcytidine Analysis Service
N4-acetyl-2'-O-methylcytidine (ac4Cm) is a modified nucleoside and an analog of cytidine. It features both methylation at the 2'-O position of the ribose and acetylation at the N4 position, providing enhanced stability to RNA molecules, particularly under high-temperature conditions. ac4Cm has been predominantly identified in thermophilic archaea, where it plays a crucial role in the organisms’ adaptation to extreme environmental conditions.
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• N4-acetylcytidine Analysis Service
N4-acetylcytidine (ac4C) is a modified nucleoside found in tRNAs and rRNAs of a wide range of organisms including bacteria, yeast, and humans. Structurally, ac4C is cytidine with an acetyl group at the 4th nitrogen position of its cytosine base. The addition of this acetyl group is facilitated by NAT10, a N-acetyltransferase enzyme in humans.
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• Hexadecanamide Analysis Service
Hexadecanamide is a long-chain amide composed of a 16-carbon fatty acid chain attached to an amide group. Its chemical formula is C16H33NO. Also known as palmitamide, hexadecanamide is synthesized from palmitic acid through amidation. It is present in various biological systems and plays a role in several important physiological processes. Hexadecanamide exhibits diverse biological activities and is significant in multiple physiological and pathological processes. It is known for its anti-inflammatory prope
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Bradykinin is a short peptide composed of nine amino acid residues, with the sequence Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg. It is generated from kininogen through the action of kallikrein. The kinin system consists of high-molecular-weight kininogen (HMWK) and low-molecular-weight kininogen (LMWK), with bradykinin primarily produced from HMWK. Bradykinin exhibits various biological activities and plays a crucial role in multiple physiological and pathological processes, particularly in vasodilation, blood pr
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• 1-Myristoyl-sn-Glycero-3-Phosphocholine Analysis Service
1-Myristoyl-sn-glycero-3-phosphocholine (1-Myr-PC) is a phospholipid molecule, and its chemical formula is C22H46NO7P. 1-Myristoyl-sn-glycero-3-phosphocholine is an important phospholipid compound that plays a crucial role in the structure and function of cell membranes. Its levels may significantly change in certain disease states, such as cancer, cardiovascular diseases, or metabolic disorders, making it a potential biomarker. Analyzing the metabolites of 1-myristoyl-sn-glycero-3-phosphocholine can reveal
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γ-Glu-Phe is a dipeptide composed of γ-glutamic acid and phenylalanine connected via an amide bond (-CONH-). γ-Glutamic acid is a variant of glutamic acid where the amino acid side chain forms a cyclic structure, which is connected to the amino group of phenylalanine. As an important amino acid, glutamic acid plays a key role in neurotransmission and amino acid metabolism. γ-Glu-Phe and its metabolites may serve as biomarkers for certain diseases or physiological states. For example, changes in its levels m
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• 3-Nitro-L-Tyrosine Analysis Service
3-Nitro-L-tyrosine is an amino acid derivative with a chemical structure composed of the amino acid tyrosine, where a nitro group (-NO₂) is attached to the third carbon of the aromatic ring. The chemical formula of 3-nitro-L-tyrosine is C₉H₁₀N₂O₅. This modification occurs through the nitration of the tyrosine residue, which can take place under oxidative stress conditions in biological systems. 3-Nitro-L-tyrosine has been recognized for its diverse biological activities and plays a significant role in vario
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