Metabolomics Analysis

• • Urea Cycle Metabolism Analysis

  The urea cycle, also known as the ornithine cycle, is a crucial metabolic pathway in the liver that converts ammonia into urea, which can then be excreted from the body. This cycle is vital for the detoxification of ammonia, a byproduct of protein metabolism, preventing its accumulation to toxic levels. Understanding the urea cycle's intricacies is essential for both human health and plant physiology, given its significant role in nitrogen metabolism.

• • Sinigrin (Allylglucosinolate) Analysis Service

  Sinigrin, also known as allylglucosinolate, is a glucosinolate compound found predominantly in plants of the Brassicaceae family, such as mustard, broccoli, and Brussels sprouts. Sinigrin consists of a glucose moiety linked to a thioglucose group and an allyl isothiocyanate side chain, which contributes to its distinctive odor and taste.

• • Indoles and Indole-Sulfur Compounds Analysis Service

  Indoles are characterized by a benzene ring fused to a pyrrole ring, with various substitutions that determine their specific biological functions. Indole-sulfur compounds, on the other hand, involve sulfur atoms incorporated into the indole structure, imparting additional chemical properties and biological activities.These compounds are found widely in nature, and exhibit significant biological activities and therapeutic potentials.

• • 3-indolepropionic Acid Analysis Service

  3-indolepropionic Acid (3-IPA), also known as indole-3-propionic acid, is a deamination product of tryptophan. It is produced by the gut microbiota and is absorbed into the bloodstream. 3-IPA has been recognized for its potent neuroprotective and antioxidant properties, making it an intriguing subject of study in the field of metabolic and gut microbiota research.

• • TMAO Quantitative Analysis Service

  Trimethylamine oxide (TMAO) is a small organic compound present in the body, and it is derived from the metabolism of dietary choline and carnitine by gut microbiota. It plays a crucial role in protein folding and protection against osmotic stress. However, recent studies showed that high levels of TMAO are associated with an increased risk of cardiovascular diseases and other metabolic disorders. Therefore, accurate quantification of TMAO is important for disease diagnosis and research purposes.

• • Oxylipins and Redox Metabolites Analysis Service

  Oxylipins are bioactive metabolites derived from the oxidative metabolism of polyunsaturated fatty acids. They play crucial roles in several biological processes such as inflammation, immunity, pain perception, and homeostasis. Redox metabolites, on the other hand, are key players in redox biology. They maintain the cellular oxidative balance, and their dysregulation is associated with several pathological conditions, including neurodegenerative diseases, cardiovascular diseases, and cancer.

• • One Carbon Metabolism Analysis

  One-carbon units are single carbon atoms that are transferred between molecules in various biochemical reactions within the cell. These units are essential in numerous metabolic processes, where they participate in the synthesis and modification of biomolecules, such as nucleotides, amino acids, and lipids. One Carbon Metabolism refers to a network of biochemical reactions that transfer one-carbon units through various enzymatic processes.

• • Central Carbon Metabolism Analysis

  Central Carbon Metabolism (CCM) governs the core biochemical transformations that provide energy and building blocks for cell growth and survival. It is an intersection of various metabolic pathways, including glycolysis, pentose phosphate pathway, TCA cycle, and anaplerotic reactions. Understanding these interrelated metabolic networks are essential in various fields, including microbial engineering, cancer research, drug discovery, and more.

• • Carnitine and Acylcarnitine Analysis Service

  Carnitines and acylcarnitines play vital roles in the oxidation of long-chain fatty acids, the degradation of branched-chain amino acids, and the removal of excess organic or amino acids. They serve as a carrier system to transport activated fatty acids from the cytosol into the mitochondria for β-oxidation. Abnormalities in carnitine and acylcarnitine metabolism are associated with numerous diseases, including metabolic disorders, neurological disorders, cancer, diabetes, and heart disease.

• • Carbohydrate Metabolism Related Products Analysis Service

  Carbohydrates are fundamental molecules in the sustenance of life, serving as key energy sources and structural components in biological systems. Their metabolism plays a crucial role in various physiological and pathological processes, including energy homeostasis, cell signaling, and diseases such as diabetes and cancer.