Metabolomics Analysis

• • Lipid Metabolism Service

  Lipids are a diverse group of biomolecules that play essential roles in cellular structure, energy storage, and signaling. They include fatty acids, triglycerides, phospholipids, sterols, and many other compounds, each with unique functions and properties. Lipids are fundamental components of cell membranes, contributing to membrane fluidity and permeability, and they serve as precursors for bioactive molecules involved in various physiological processes.

• • Glycosylphosphatidylinositol Anchor Analysis Service

  Glycosylphosphatidylinositol (GPI) anchors are glycolipids that attach to the C-terminus of proteins, serving to anchor these proteins to the cell membrane. They play a critical role in a wide range of biological processes including signal transduction, protein sorting, and host-pathogen interactions, among others. Mutations in the GPI anchor biosynthesis pathway can lead to a group of disorders known as GPI anchor deficiencies (GPIBDs), which have severe clinical implications.

• • Various Types of N-glycan Analysis Service

  N-glycosylation is one of the most important and complex post-translational modifications (PTMs) that plays crucial roles in various biological processes. N-glycans are complex carbohydrate structures covalently attached to proteins through N-linked glycosidic bonds, typically occurring at asparagine residues within the consensus sequon Asn-X-Ser/Thr.

• • Ganglio Series of Glycosphingolipid Analysis Service

  Gangliosides are complex molecules consisting of glycosphingolipids, which include ceramide and oligosaccharides, attached to one or more sialic acids such as N-acetylneuraminic acid (NANA). These molecules are found in the plasma membrane, particularly concentrated in the nervous system, where they play crucial roles in modulating cell signal transduction.

• • Quinolinic Acid Analysis Service

  Quinolinic Acid, also known as quinolinate, is a significant metabolite derived from tryptophan with numerous vital roles in human physiology and pathology. Abnormal concentrations of quinolinic acid are linked to various disorders, notably neurodegenerative diseases as well as cardiovascular diseases. Consequently, the precise and efficient quantification of quinolinic acid is essential for early disease detection and therapeutic interventions.

• • Nicotinamide Adenine Dinucleotide Phosphate Analysis Service

  Nicotinamide adenine dinucleotide phosphate (NADP) and its reduced form (NADPH) are crucial coenzymes in many biosynthetic pathways, involved in everything from lipid and nucleic acid synthesis to the detoxification of free radicals. At MtoZ Biolabs, we understand the importance of detailed and accurate analysis of these molecules. We are excited to introduce our Nicotinamide Adenine Dinucleotide Phosphate Analysis Service.

• • Adenosine Triphosphate Analysis Service

  Adenosine triphosphate (ATP), present in all known life forms, serves as the essential "molecular currency" for intracellular energy transfer. During metabolic activities, ATP is converted into adenosine diphosphate (ADP) or adenosine monophosphate (AMP), both of which can be subsequently regenerated back to ATP through various biochemical pathways. As a fundamental precursor for RNA and DNA synthesis, ATP also acts as a coenzyme.

• • Phosphoenolpyruvate Analysis Service

  Phosphoenolpyruvate (PEP) is a carboxylic acid that forms through the transformation of pyruvate’s enol form, combined with phosphate. It primarily exists in its anionic form in biological systems. It is a key metabolite involved in many biochemical pathways, including glycolysis and gluconeogenesis.  As a crucial biochemical intermediate, PEP possesses one of the most high-energy phosphate bonds in organisms.

• • Dihydroxyacetone Phosphate Analysis Service

  Dihydroxyacetone phosphate (DHAP) is an anion represented by the chemical formula HOCH₂C(O)CH₂OPO₃²⁻. It is a crucial metabolic intermediate in Calvin cycle, glycolysis and lipid metabolism, playing a vital role in numerous biological processes. Accurate, reliable, and sensitive analysis of DHAP is essential for understanding its function in metabolism and disease development.

• • Isocitric Acid Analysis Service

  Isocitrate, a structural isomer of citrate, shares similar physical and chemical properties with its counterpart. It is a critical metabolic product of the tricarboxylic acid cycle (TCA), where it significantly contributes to energy generation and the provision of carbon skeletons essential for various biosynthetic processes. Deviations in isocitrate levels are associated with numerous metabolic disorders, underscoring the importance of its accurate measurement for diagnosing diseases...