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    Metanephrine Analysis Service

      Metanephrine is a metabolite formed from epinephrine (also known as adrenaline) through methylation. Epinephrine is a key catecholamine hormone and neurotransmitter that plays a crucial role in regulating blood pressure, heart rate, metabolism, and the body's stress response. Metanephrine is the methylated product of epinephrine, characterized by the addition of a methyl group to the structure of epinephrine. Metanephrine is commonly found in biological systems as an important intermediate product of epinephrine metabolism.

       

      Due to its significance in epinephrine metabolism, metanephrine is involved in various physiological processes, including the regulation of stress response, vasoconstriction, and energy metabolism. However, abnormally elevated levels of metanephrine are often associated with certain diseases, such as pheochromocytoma (a tumor of the adrenal medulla) and paraganglioma, which cause excessive release of catecholamines. The quantitative analysis of metanephrine and its related metabolites is essential for diagnosing and monitoring these diseases, helping to assess the state of catecholamine metabolism and identify potential endocrine disorders. Additionally, analyzing metanephrine levels can help evaluate the effectiveness of treatment strategies, such as surgical intervention or pharmacological therapy in patients with abnormal catecholamine metabolism.

       

      1831940363431563264-TheStructureofMetanephrine.png

      Figure 1. The Structure of Metanephrine

       

      At MtoZ Biolabs, we are proud to offer you our superior Metanephrine Analysis Service. Utilizing our top-of-the-line liquid chromatography-mass spectrometry (LC-MS) platform and an experienced metabolomics team, we are confident to provide you with the most accurate and sensitive analysis of metanephrine.

       

      Analysis Workflow

       

      1831940425683423232-WorkflowofMetanephrineAnalysisService.PNG

       

      Service Advantages

      1. Continuously refined protocols and cutting-edge analytical tools  

       

      2. Expert experimental planning  

       

      3. Rapid processing times  

       

      4. Exceptional precision, selectivity, and sensitivity

       

      Applications

      • Qualitative analysis of the metabolites of metanephrine
      • Quantitative analysis of metanephrine content
      • Clinical biomarker research
      • Medical and pharmaceutical research

       

      Sample Submission Requirements

      1. Sample Types

      Serum, plasma, urine, tissues, and other biological samples. Please ensure to provide at least 3 materials of the same condition for each sample.

       

      2. Sample Volume

      • Animal tissue ≥ 100 mg
      • Plant tissue ≥ 200 mg
      • Serum/ Plasma ≥ 200 μL
      • Urine ≥ 2 mL

       

      3. Sample Preservation

      Store at -80°C to maintain the sample stability.

       

      Note: Please provide detailed information on sample collection and handling.

       

      Deliverables

      1. Experimental Procedures

      2. Relevant Liquid Chromatography and Mass Spectrometry Parameters

      3. Detailed Information on Metanephrine

      4. Raw Data

      5. Custom Analysis Report

       

      Our mission is to expedite your research and product development by delivering highly accurate and reliable results through our Metanephrine Analysis Service.

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