N2-methylguanosine Analysis Service
- State-of-the-art LC-MS/MS platforms allow us to accurately and reliably quantify N2-methylguanosine in various types of samples.
- A team of experts in mass spectrometry and metabolomics provides professional data analysis and interpretation.
- One-stop service from sample preparation, LC-MS/MS analysis to data analysis, saving your time and efforts.
- Competitive price with high-quality service.
- Molecular biology
- Disease biomarker discovery
- Drug development
- Animal tissue ≥ 100 mg
- Plant tissue ≥ 200 mg
- Serum/ Plasma ≥ 200 μL
- Urine ≥ 2 mL
N2-Methylguanosine (m2G) is a modified nucleoside characterized by the methylation of the nitrogen atom at the 2-position of the guanine base. This modification is primarily found in transfer RNA (tRNA), where it contributes significantly to the structural stability and functional efficiency of RNA molecules. Elevated levels of m2G have been associated with cellular stress responses and can serve as indicators of specific pathological conditions, including cancer and metabolic disorders. The study of N2-methylguanosine is crucial for elucidating the complexities of RNA modifications and their impact on cellular physiology. As researchers seek to unravel the roles of RNA modifications in health and disease, the accurate quantification and characterization of m2G become increasingly important.
Figure 1. The Structure of N2-methylguanosine
At MtoZ Biolabs, we offer a comprehensive N2-methylguanosine analysis service backed by our rich expertise in mass spectrometry and metabolomics. We offer in-depth analysis of N2-methylguanosine through our state-of-the-art mass spectrometry platform. We can assist in determining the location and quantity of m2G in the tRNA molecule, elucidate its metabolic pathway, and uncover its association with disease.
Analysis Workflow
Service Advantages
Applications
Our N2-methylguanosine analysis service can be applied in the following research areas:
Sample Submission Requirements
1. Sample Types
Serum, plasma, urine, tissues, and other biological samples. It is recommended to prepare at least 3 biological replicates for each sample type.
2. Sample Volume
3. Storage and Shipping
Samples should be stored at -80℃ and shipped with dry ice. Avoid repeated cycles of freezing and thawing
Note: Please provide details on sample collection and handling.
Deliverables
1. Experimental Procedures
2. Relevant Liquid Chromatography and Mass Spectrometry Parameters
3. Detailed Information on N2-methylguanosine
4. Raw Data
5. Custom Analysis Report
Contact us today to learn more about our N2-methylguanosine analysis service. At MtoZ Biolabs, we are committed to providing high-quality, reliable, and professional service to accelerate your research.
How to order?
