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    Oncology Research Metabolomics Service

      Cancer is a serious global health problem. The challenge of understanding and treating cancer lies in its complexity and diversity. The occurrence, development, and metastasis of cancer involve changes in metabolites, so metabolomics plays a crucial role in cancer research. Metabolomics can provide comprehensive information on biological samples, which is of great significance for revealing the mechanism of cancer occurrence, discovering potential biomarkers, and drug development.

       

      A-schematic-representation-of-untargeted-metabolomics-based-cancer-biomarker-discovery.png

      Taunk, K. Mol Cell Biochem. 2024.

      Figure1. A Schematic Representation of Untargeted Metabolomics-based Cancer Biomarker Discovery Workflow 

       

      Services at MtoZ Biolabs

      MtoZ Biolabs provides comprehensive metabolomics solutions for oncology research with cutting-edge mass spectrometry technology and professional data processing capabilities. Our research can help reveal the metabolic characteristics of tumors, discover new tumor biomarkers, assess drug efficacy, thereby providing a basis for early diagnosis and treatment of tumors.

       

      1. Metabolomics research of cancer occurrence mechanism

      By comparing the differences in metabolites between cancerous tissues and normal tissues to reveal the metabolic mechanism of cancer occurrence.

       

      2. Discovery of cancer biomarkers

      By comparing the differences in metabolites in blood, urine, and other body fluids between cancer patients and healthy people to discover potential cancer biomarkers.

       

      3. Metabolomics research of drug action mechanism

      By comparing the differences in metabolites in cancerous tissues or body fluids before and after drug treatment to reveal the mechanism of drug action.

       

      Experimental Instruments

      Our technology platform includes GC-MS, LC-MS, UPLC-MS, etc., to carry out all-round analysis of thousands of metabolites in the sample, providing a comprehensive and in-depth understanding for cancer research.

       

      1. Chromatography Technology

      • GC-MS (Q Exactive) (- mode MS)
      • HPLC: HILIC (+/- mode MS)
      • HPLC: RP C18 (+/- mode MS)
      • IC (- mode MS)

       

      2. Mass Spectrometry Technology

      • Q Exactive MS
      • Orbitrap Tribrid Mass Spectrometer

       

      Sample Submission Requirements

      1. Sample Type: Blood, urine, tissue, etc.

      2. Sample Quantity: No less than 1ml for blood, no less than 2ml for urine, and no less than 50mg for tissue.

      3. Sample Storage: Frozen at -80℃.

       

      MtoZ Biolabs has extensive experience in metabolomics analysis, and our technical team will provide personalized solutions according to your research needs. If you need more information, please contact us. We look forward to cooperating with you.

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