Phospho-proteomics

Phospho-proteomics is an advanced technique for studying the phosphorylation states of proteins and their roles in biological processes. Protein phosphorylation is a crucial regulatory mechanism in various biological processes, including cell signaling, metabolic regulation, cell cycle control, and intercellular communication. Phosphorylation modifies proteins by adding or removing phosphate groups, thereby regulating protein activity, localization, and interactions, which influence cellular functions and physiological states.

 

Phospho-proteomics employs high-throughput technology and precise quantitative analysis to reveal dynamic changes in cellular signaling pathways, molecular mechanisms, and disease-related regulatory networks. Recent advancements in phospho-proteomics have significantly contributed to research on cancer, neurodegenerative diseases, cardiovascular diseases, and immune disorders. By thoroughly analyzing protein phosphorylation states, we can gain deeper insights into the mechanisms of disease development and progression, identify potential biomarkers, and discover therapeutic targets. Therefore, phospho-proteomics analysis is vital in biomedical research.

 

 

Figure 1. Schematic Diagram of Protein Phosphorylation

 

MtoZ Biolabs offers phospho-proteomics services using advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS). This technology combines the high separation capability of high-performance liquid chromatography with the high sensitivity of mass spectrometry, enabling efficient and accurate identification and quantification of phosphorylated proteins.

 

Analysis Workflow

 



 

Service Advantages

 



 

Sample Submission Requirements

 



For detailed sample submission instructions, please consult our technical team.

 

Applications

1. Disease Mechanism Research: Revealing molecular mechanisms of diseases such as cancer, cardiovascular diseases, and neurodegenerative diseases.

 

2. Drug Development: Screening potential drug targets and evaluating the impact of drugs on signaling pathways.

 

3. Cell Signaling Research: Studying dynamic changes in intracellular signaling pathways.

 

4. Biomarker Discovery: Identifying phosphorylated protein biomarkers related to disease diagnosis and prognosis.

 

MtoZ Biolabs is dedicated to providing high-quality phospho-proteomics analysis services. Our technology and team can meet your diverse research needs and provide reliable support for your scientific exploration. Contact us for more details or inquiries. We look forward to collaborating with you to advance scientific research and technology.