Protein Benzoylation Analysis

Protein benzoylation is a novel lysine acylation modification that uniquely involves the attachment of a benzoyl group. As the only known lysine modification with a benzene ring, benzoylation is distinct from traditional acetylation. The benzoyl group is significantly larger, approximately twice the size of an acetyl group, and exhibits nearly three times the hydrophobicity. Each benzoylation event increases the protein’s molecular weight by 104.0268 Da. This modification has profound effects on protein structure and function, particularly on histones, where it can influence gene expression and chromatin structure more strongly than acetylation. Additionally, benzoylation can also play crucial regulatory roles in non-histone proteins. 

 

 

Figure 1. Lysine Benzoylation

 

Leveraging state-of-the-art mass spectrometry and advanced proteomic analysis, MtoZ Biolabs offers highly sensitive Protein Benzoylation Analysis services to help researchers investigate this emerging modification and its diverse biological functions.

 

Analysis Workflow

 

 

 

Services at MtoZ Biolabs

1. Targeted Protein Benzoylation Analysis

MtoZ Biolabs offers specialized analysis services to detect and quantify benzoylation modifications on specific target proteins. Using high-sensitivity mass spectrometry, we accurately identify benzoylation sites and quantify their levels, helping to uncover their roles in both normal and pathological states. Our service includes precise identification of modification sites, quantitative analysis, and comprehensive functional bioinformatics annotation, enabling researchers to gain deeper insights into protein regulation.

 

2. Benzoylation Proteomics

Our benzoylation proteomics service offers a comprehensive approach to identifying and quantifying benzoylation modifications across the proteome. Using the LC-MS/MS platform and specific antibodies, we conduct large-scale, high-throughput analyses to detect benzoylation patterns across different tissues or conditions. This service also includes detailed proteomics-level data reports and personalized functional annotation, allowing researchers to explore the broader implications of benzoylation in biological systems.

 

Service Advantages

Why Choose MtoZ Biolabs?

1. Advance Analysis Platform: MtoZ Biolabs established an advanced protein PTM analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate PTM proteomics analysis data providing clients with a comprehensive data report.

4. Wide Applicability: Suitable for various biological samples, including blood, urine, and tissues.

5. Customized Solutions: We offer tailored services, from modification site identification to in-depth functional annotation, providing customized support to meet specific research objectives.

 

Sample Submission Requirements

 



For more sample details, please consult our technical team.

 

Deliverables

What Could be Included in the Report?

1. Comprehensive Experimental Details

2. Materials, Instruments, and Methods

3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)

4. Data Analysis, Preprocessing, and Estimation (project-dependent)

5. Bioinformatics Analysis

6. Raw Data Files

 

At MtoZ Biolabs, we are committed to delivering high-quality, high-throughput Protein Benzoylation Analysis services to help researchers unravel the complex regulatory mechanisms of post-translational modifications. Our expertise in proteomics and metabolomics positions us at the forefront of scientific discovery. For more information or inquiries, please contact us.