Protein Diglycylation Analysis
- DNA damage repair research
- Disease mechanism investigation
- Immune regulation studies
- Protein degradation pathway analysis
Protein post-translational modifications (PTMs) are essential for the regulation of cellular functions and signaling pathways. Protein diglycylation is a distinct PTM that occurs in the ubiquitination pathway, typically at lysine residues. Diglycylation results from the activity of deubiquitinases in the ubiquitin-proteasome system, leaving behind a diglycine remnant after cleavage of ubiquitin chains. This modification plays a significant regulatory role in processes such as the cell cycle, DNA damage repair, protein degradation, and immune responses. Growing research has linked diglycylation to the development of various diseases, including cancer, neurodegenerative disorders, and immune system dysregulation. Analyzing protein diglycylation is therefore crucial to understanding its impact on biological functions and disease mechanisms.
MtoZ Biolabs offers highly sensitive and specific Protein Diglycylation Analysis services, leveraging advanced liquid chromatography-mass spectrometry (LC-MS/MS) platforms. Our services allow for precise detection of diglycylation sites, helping researchers gain deeper insights into the functions and regulatory mechanisms of this modification in diverse biological contexts.
Analysis Workflow
Services at MtoZ Biolabs
1. Targeted Protein Diglycylation Analysis
MtoZ Biolabs offers targeted analysis for protein diglycylation using immune enrichment and high-resolution mass spectrometry. This service precisely detects diglycylation sites on specific proteins, ensuring both high sensitivity and accurate quantification, making it ideal for detailed studies of specific targets.
2. Diglycylation Proteomics
Our Protein Diglycylation Proteomics service leverages high-throughput mass spectrometry to perform a comprehensive analysis of diglycylation modifications across the proteome. It generates a detailed modification map, revealing global modification patterns, and is designed for large-scale sample studies.
Service Advantages
Why Choose MtoZ Biolabs?
1. Advance Analysis Platform: MtoZ Biolabs established an advanced protein PTM analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.
2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.
3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate PTM proteomics analysis data providing clients with a comprehensive data report.
4. Flexible Quantitative Analysis: We provide both TMT/iTRAQ labeling and Label-Free quantification methods, catering to diverse research needs.
5. Comprehensive Site Identification: We simultaneously identify multiple diglycylation sites, delivering a detailed map of protein modifications.
Applications
Deliverables
1. Comprehensive Experimental Details
2. Materials, Instruments, and Methods
3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)
4. Data Analysis, Preprocessing, and Estimation (project-dependent)
5. Bioinformatics Analysis
6. Raw Data Files
MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details!
How to order?
