Protein Dimethylation Analysis

Protein dimethylation is a common form of post-translational modification (PTM), typically involving the methylation of lysine (Lys) or arginine (Arg) residues. Compared to monomethylation and trimethylation, dimethylation plays a crucial role in regulating gene expression, modifying chromatin structure, and mediating signal transduction. Protein dimethylation is divided into asymmetric dimethylation and symmetric dimethylation, each serving distinct functions in various biological processes. Asymmetric dimethylation is particularly important in RNA metabolism and immune responses, while symmetric dimethylation primarily influences chromatin remodeling and gene regulation.

 




Figure 1. Lysine Dimethylation

 

MtoZ Biolabs, with its advanced mass spectrometry platform and extensive experience in PTM analysis, offers comprehensive Protein Dimethylation Analysis services. Utilizing high-resolution mass spectrometry and enrichment techniques, we accurately identify and quantify dimethylation sites, enabling researchers to explore the regulatory roles of dimethylation in cellular metabolism, gene expression, and disease pathways.

 

Analysis Workflow

 

Services at MtoZ Biolabs

1. Targeted Protein Dimethylation Analysis

MtoZ Biolabs provides targeted protein dimethylation analysis, offering precise identification and quantification of dimethylation modifications on specific proteins. This service supports research into gene regulation, cell cycle control, and disease mechanisms, and is widely applied in the fields of cancer, metabolic diseases, and signal transduction.

 

2. Dimethylation Proteomics

MtoZ Biolabs’ protein dimethylation proteomics service enables comprehensive analysis of dimethylation modifications across the proteome using mass spectrometry. This service delivers a detailed modification map, uncovering the roles of dimethylation in metabolism, gene expression, and disease mechanisms, and is well-suited for large-scale studies in epigenetics and metabolomics.

 

Service Advantages

Why Choose MtoZ Biolabs?

1. Advance Analysis Platform: MtoZ Biolabs established an advanced protein PTM analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate PTM proteomics analysis data providing clients with a comprehensive data report.

4. Multi-Sample Compatibility: Our platform supports a wide variety of biological samples, including cells, tissues, blood, and bodily fluids, providing flexibility to accommodate diverse research demands.

5. Customized Service: Tailored to the specific research needs of our clients, we offer flexible experimental design and personalized data analysis to ensure the achievement of research goals to the fullest extent.

 

Sample Submission Requirements

 



For more sample details, please consult our technical team.

 

Deliverables

What Could be Included in the Report?

1. Comprehensive Experimental Details

2. Materials, Instruments, and Methods

3. Total Ion Chromatogram & Quality Control Assessment (project-dependent)

4. Data Analysis, Preprocessing, and Estimation (project-dependent)

5. Bioinformatics Analysis

6. Raw Data Files

 

MtoZ Biolabs, an integrated Chromatography and Mass Spectrometry (MS) Services Provider, provides advanced proteomics, metabolomics, and biopharmaceutical analysis services to researchers in biochemistry, biotechnology, and biopharmaceutical fields. Our ultimate aim is to provide more rapid, high-throughput, and cost-effective analysis, with exceptional data quality and minimal sample consumption. Free project evaluation, welcome to learn more details!