Protein Trimethylation Analysis

Post-translational modifications (PTMs) refer to the chemical alterations that occur to proteins either during or after translation. PTMs are essential in regulating numerous cellular processes, including cell differentiation, protein degradation, signal transduction, gene expression regulation, and protein-protein interactions. Protein trimethylation, a key post-translational modification, involves the covalent attachment of three methyl groups (-CH₃) to specific residues, typically lysine or arginine. Trimethylation plays critical biological roles, particularly in gene regulation, epigenetic modulation, and signal transduction pathways. Comprehensive analysis of protein trimethylation (target protein trimethylation analysis and trimethylation proteomics) not only enhances our understanding of fundamental cellular processes but also identifies promising therapeutic targets for diseases such as cancer.

 

Services at MtoZ Biolabs

MtoZ Biolabs utilizes Thermo Fisher's Q Exactive HF, Orbitrap Fusion, and Orbitrap Fusion Lumos mass spectrometry platforms, in combination with Nano-LC, to offer a comprehensive solution for protein trimethylation analysis, which include target protein trimethylation analysis and trimethylation proteomics. Simply provide us with your experimental objectives and sample materials, and we will manage the entire workflow, delivering detailed identification and quantification of trimethylation modifications on specific proteins and a panoramic view of trimethylation modifications across various samples, uncovering extensive trimethylation patterns. If you are interested in our protein trimethylation analysis service, please feel free to contact us. We are dedicated to providing you with the best service.

 

Analysis Workflow

 



 

Service Advantages

1. Advance Analysis Platform: Mtoz Biolabs established an advanced protein trimethylation analysis platform, guaranteeing reliable, fast, and highly accurate analysis service.

 

2. One-Time-Charge: Our pricing is transparent, no hidden fees or additional costs.

 

3. High-Data-Quality: Deep data coverage with strict data quality control. AI-powered bioinformatics platform integrate all protein trimethylation analysis data providing clients with acomprehensive data report.

 

4. Comprehensive Analysis: Both target protein trimethylation analysis and trimethylation proteomics can be conducted in MtoZ Biolabs.

 

Sample Submission Requirements

 



1. If you are providing tissue samples, please ship them to us on dry ice.

 

2. If you are providing protein samples, standard tissue or cell lysis buffers can be used during protein extraction.

 

3. Sample transportation: Please ensure that samples are shipped with sufficient dry ice and choose the fastest possible shipping way to minimize the risk of sample degradation during transit.

 

4. Before proceeding with the formal experiment, we will test the samples you provide, and the formal analysis will begin once the samples pass the quality check.

 

Deliverables

1. Comprehensive Experimental Details

2. Materials, Instruments, and Methods

3. The Detailed Information of Protein Trimethylation Analysis

4. Mass Spectrometry Image

5. Bioinformatics Analysis

6. Raw Data